Evidence map›Paper›PMID 41350978›Full record

ArticleBMC cardiovascular disorders2025

Association between left ventricle diastolic dysfunction and circadian blood pressure pattern in arterial hypertension.

I U Ekanayake, N V Bukvalnaya, L N Smirnova, S J N Siddiarachchi, S L Ekanayake, A P Vitharana, L V Yakubova

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Article in BMC cardiovascular disorders, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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4 · The record

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5 · Who and what money

Authors and funding

7 authors.

I U EkanayakeCeylon Institute for Artificial Intelligence and Research, Colombo, Sri Lanka. Imesh@ciair.org.
N V BukvalnayaDepartment of General Medical Practice and Outpatient Therapy, Grodno State Medical University, Grodno, Belarus.
L N SmirnovaDepartment of General Medical Practice and Outpatient Therapy, Grodno State Medical University, Grodno, Belarus.
S J N SiddiarachchiCeylon Institute for Artificial Intelligence and Research, Colombo, Sri Lanka.
S L EkanayakeCeylon Institute for Artificial Intelligence and Research, Colombo, Sri Lanka.
A P VitharanaCeylon Institute for Artificial Intelligence and Research, Colombo, Sri Lanka.
L V YakubovaDepartment of General Medical Practice and Outpatient Therapy, Grodno State Medical University, Grodno, Belarus.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveTo assess the relationship between left ventricular diastolic dysfunction (LVDD) and circadian blood pressure (BP) pattern in arterial hypertension (AH).

methodsA total of 96 patients with AH of I-II grades were examined. Transthoracic echocardiography was performed using a high-end ultrasound device GE Vivid 7 Pro (USA). 24-hour Ambulatory BP Monitoring was carried out using a Microlife Watch BP 03 device on the non-dominant arm. Statistical analysis of the obtained results was carried out using the Statistica 10.0 application package.

resultsAfter echocardiography all patients were divided into two groups. The first group is patients with AH and LVDD (n = 37), second group is patients with AH without LVDD (n = 59). The dipper pattern of systolic BP (SBP) was significantly more common in patients in the second group (p = 0.014). The non-dipper pattern of diastolic BP (DBP) was significantly more common in patients of group 1 (p = 0.047). The odds ratio of LVDD developing in patients with AH and a non-dipper pattern of SBP and DBP was 2.907 (95% confidence interval (CI) 1.233–6.852) and 3.329 (95% CI 1.346–8.234), respectively.

conclusionA non-dipper pattern of SBP and DBP was significantly associated with LVDD and may be a therapeutic target for preservation of the diastolic function.

Indexed as

Arterial PressureBlood PressureCircadian RhythmHypertensionVentricular Dysfunction, LeftVentricular Function, LeftAgedBlood Pressure Monitoring, AmbulatoryDiastoleFemaleHumansMaleMiddle AgedRisk FactorsTime FactorsArterial hypertensionEchocardiographic parametersLeft ventricular diastolic dysfunctionNon-dipper pattern

Identifiers

PMID41350978
PMCPMC12797718

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.