Evidence map›Paper›PMID 41350974›Full record

ArticleMolecular imaging and biology2026

Molecular Insights into BZW1 Expression and [

Jiahe Li, Siqi Wang, Guangfang Chen, Yiyi Hu, Hongliang Wang, Hua Wei, Haiyan Liu, Caozhe Cui, Yayuan Li, Xiaomeng Li and 3 more

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Article in Molecular imaging and biology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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1 · What the graph read from it

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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

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3 · Its place in the literature

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4 · The record

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5 · Who and what money

Authors and funding

13 authors.

Jiahe LiDepartment of Nuclear Medicine, First Hospital of Shanxi Medical University, Taiyuan, Shanxi, 030001, People's Republic of China.
Siqi WangDepartment of Nuclear Medicine, First Hospital of Shanxi Medical University, Taiyuan, Shanxi, 030001, People's Republic of China.
Guangfang ChenDepartment of Nuclear Medicine, First Hospital of Shanxi Medical University, Taiyuan, Shanxi, 030001, People's Republic of China.
Yiyi HuDepartment of Nuclear Medicine, First Hospital of Shanxi Medical University, Taiyuan, Shanxi, 030001, People's Republic of China.
Hongliang WangDepartment of Nuclear Medicine, First Hospital of Shanxi Medical University, Taiyuan, Shanxi, 030001, People's Republic of China.
Hua WeiDepartment of Nuclear Medicine, First Hospital of Shanxi Medical University, Taiyuan, Shanxi, 030001, People's Republic of China.
Haiyan LiuDepartment of Nuclear Medicine, First Hospital of Shanxi Medical University, Taiyuan, Shanxi, 030001, People's Republic of China.
Caozhe CuiDepartment of Nuclear Medicine, First Hospital of Shanxi Medical University, Taiyuan, Shanxi, 030001, People's Republic of China.
Yayuan LiDepartment of Nuclear Medicine, First Hospital of Shanxi Medical University, Taiyuan, Shanxi, 030001, People's Republic of China.
Xiaomeng LiDepartment of Nuclear Medicine, First Hospital of Shanxi Medical University, Taiyuan, Shanxi, 030001, People's Republic of China.
Xinchao WangDepartment of Nuclear Medicine, First Hospital of Shanxi Medical University, Taiyuan, Shanxi, 030001, People's Republic of China.
Jianbo CaoDepartment of Nuclear Medicine, First Hospital of Shanxi Medical University, Taiyuan, Shanxi, 030001, People's Republic of China. caojianbo272@gmail.com.
Zhifang WuDepartment of Nuclear Medicine, First Hospital of Shanxi Medical University, Taiyuan, Shanxi, 030001, People's Republic of China. zhifangwu@sxmu.edu.cn.ORCID http://orcid.org/0000-0003-0376-982X

Funding

National Natural Science Foundation of China Nos. 82027804Natural Science Foundation for Young Scientists of Shanxi Province No.202203021212048Shanxi Province Higher Education "Billion Project" Science and Technology Guidance Project BYYX001Shanxi Province Higher Education "Billion Project" Science and Technology Guidance Project BYYX003
6 · The paper itself

Abstract

purposeEarly detection and intervention in lung adenocarcinoma (LUAD) are critical for improving patient prognosis. This study explores the role of basic leucine zipper and W2 domains 1 (BZW1, BZAP45) in regulating malignant cellular behavior and glycolytic metabolism in LUAD. PROCEDURES: Bioinformatics and clinical information analysis was conducted to study BZW1 expression and its relationship with prognosis, glycolysis-related genes expression and PET/CT parameters of 2-deoxy-2-[

resultsBioinformatic analyses identified BZW1 as a pivotal gene driving LUAD progression. The retrospective analysis revealed that BZW1 expression is elevated in LUAD tissues and is significantly correlated with clinical tumor parameters and metabolic parameters obtained from [

conclusionsThese findings highlighted the role of BZW1 in LUAD metabolism and may promote tumor progression through modulating of glycolytic pathways. In conclusion, BZW1 is significantly associated with LUAD malignancy and [

Indexed as

Adenocarcinoma of LungFluorodeoxyglucose F18Lung NeoplasmsPositron Emission Tomography Computed TomographyA549 CellsAnimalsCell Line, TumorCell MovementCell ProliferationFemaleGene Expression Regulation, NeoplasticGlycolysisHumansMaleMiceMice, Inbred BALB CFluorodeoxyglucose F18[18F]FDGBZW1GlycolysisLung adenocarcinomaPET/CT

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.