Evidence map›Paper›PMID 41350951›Full record

ArticleEuropace : European pacing, arrhythmias, and cardiac electrophysiology : journal of the working groups on cardiac pacing, arrhythmias, and cardiac cellular electrophysiology of the European Society of Cardiology2025

Pre-procedural computed tomography predicts procedural complexity and complications in bidirectional rotational mechanical transvenous lead extraction.

Federico Migliore, Raimondo Pittorru, Vincenzo Tarzia, Jacopo Rosso, Manuel De Lazzari, Andrea Ziggiotto, Gaia Zancanaro, Giulia Winnicki, Marco Gemelli, Matteo Micciolo and 6 more

Abstract read
In one paragraph

Article in Europace : European pacing, arrhythmias, and cardiac electrophysiology : journal of the working groups on cardiac pacing, arrhythmias, and cardiac cellular electrophysiology of the European Society of Cardiology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

16 authors.

Federico MiglioreDepartment of Cardiac, Thoracic, Vascular Sciences and Public Health, University of Padova, Via N. Giustiniani 2, Padua 35121, Italy.ORCID 0000-0001-8574-9421
Raimondo PittorruDepartment of Cardiac, Thoracic, Vascular Sciences and Public Health, University of Padova, Via N. Giustiniani 2, Padua 35121, Italy.ORCID 0009-0007-8824-4868
Vincenzo TarziaDepartment of Cardiac, Thoracic, Vascular Sciences and Public Health, University of Padova, Via N. Giustiniani 2, Padua 35121, Italy.
Jacopo RossoDepartment of Cardiac, Thoracic, Vascular Sciences and Public Health, University of Padova, Via N. Giustiniani 2, Padua 35121, Italy.
Manuel De LazzariDepartment of Cardiac, Thoracic, Vascular Sciences and Public Health, University of Padova, Via N. Giustiniani 2, Padua 35121, Italy.ORCID 0000-0001-8926-187X
Andrea ZiggiottoDepartment of Cardiac, Thoracic, Vascular Sciences and Public Health, University of Padova, Via N. Giustiniani 2, Padua 35121, Italy.
Gaia ZancanaroDepartment of Cardiac, Thoracic, Vascular Sciences and Public Health, University of Padova, Via N. Giustiniani 2, Padua 35121, Italy.
Giulia WinnickiDepartment of Cardiac, Thoracic, Vascular Sciences and Public Health, University of Padova, Via N. Giustiniani 2, Padua 35121, Italy.ORCID 0009-0006-6092-9884
Marco GemelliDepartment of Cardiac, Thoracic, Vascular Sciences and Public Health, University of Padova, Via N. Giustiniani 2, Padua 35121, Italy.ORCID 0000-0003-2902-7947
Matteo MiccioloDepartment of Cardiac, Thoracic, Vascular Sciences and Public Health, University of Padova, Via N. Giustiniani 2, Padua 35121, Italy.
Antonio GuerrieriRadiology Unit, University of Padua-Azienda Ospedaliera, Padua, Italy.
Davide MargheriRadiology Unit, University of Padua-Azienda Ospedaliera, Padua, Italy.ORCID 0009-0004-3379-0704
Raffaella MottaDepartment of Cardiac, Thoracic, Vascular Sciences and Public Health, University of Padova, Via N. Giustiniani 2, Padua 35121, Italy.ORCID 0000-0002-1886-9826
Valeria PergolaDepartment of Cardiac, Thoracic, Vascular Sciences and Public Health, University of Padova, Via N. Giustiniani 2, Padua 35121, Italy.ORCID 0000-0002-3317-7342
Gino GerosaDepartment of Cardiac, Thoracic, Vascular Sciences and Public Health, University of Padova, Via N. Giustiniani 2, Padua 35121, Italy.ORCID 0000-0002-6261-699X
Domenico CorradoDepartment of Cardiac, Thoracic, Vascular Sciences and Public Health, University of Padova, Via N. Giustiniani 2, Padua 35121, Italy.ORCID 0000-0003-1487-0392

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

aimsDespite technical advances, transvenous lead extraction (TLE) remains a challenging procedure. Cardiac computed tomography (CT) has emerged as a valuable tool for pre-procedural assessment, but its role in predicting outcomes in rotational mechanical TLE as a first-line strategy is not well defined. The aim was to determine whether pre-procedural CT can predict complications and procedural complexity in patients undergoing rotational mechanical TLE. METHODS AND

resultsThis retrospective study included 115 patients. All had pre-procedural contrast-enhanced CT with a dedicated lead extraction protocol. Two procedural outcomes were evaluated: (i) complicated procedure, defined as major complication, incomplete lead removal, or snare use, and (ii) complex procedure, defined as requiring either a snare or a tissue stabilization sheath. Logistic regression and receiver operating characteristic analyses were used to identify predictors. A total of 215 leads were extracted (mean dwelling time 95 ± 73 months). Complicated procedures occurred in 20.9% and were independently associated with longest fibrosis length on CT (odds ratio 1.1; P < 0.001); a fibrosis length of >40 mm predicted complicated procedures [area under the curve (AUC) 0.92; 95% confidence interval (CI) 0.88-0.97]. Complex procedures occurred in 37.4% and were associated with longest fibrosis length, lead calcification, dwelling time, and systolic heart failure. A fibrosis length of >30 mm predicted complex procedures (AUC 0.72; 95% CI 0.64-0.81).

conclusionPre-procedural CT allows accurate identification of high-risk anatomical features, particularly fibrosis length and calcifications, which independently predict both complicated and complex rotational mechanical TLE. These findings support the integration of CT imaging into procedural planning and individualized risk stratification.

Indexed as

Defibrillators, ImplantableDevice RemovalPacemaker, ArtificialPostoperative ComplicationsTomography, X-Ray ComputedAgedAged, 80 and overDevice Lead ExtractionFemaleHumansMaleMiddle AgedPredictive Value of TestsRetrospective StudiesRisk FactorsROC CurveComplicationsComputed tomographyRisk stratificationRotational mechanical sheaths

Identifiers

PMID41350951
PMCPMC12757581

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.