Evidence map›Paper›PMID 41350949›Full record

ArticleMolecular neurobiology2025

Systematic Phenotyping and Molecular Analysis of the Woozy Mouse: A Preclinical Model of Cerebellar Ataxia.

Fabio Bellia, Laura Amodei, Anna Giulia Ruggieri, Francesca Potenza, Marianna Viele, Manuela Bomba, Francesco Del Pizzo, Manuela Iezzi, Alberto Granzotto, Luca Federici and 1 more

Erratum issuedAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Molecular neurobiology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

11 authors.

Fabio BelliaCenter for Advanced Studies and Technology (CAST), "G. d'Annunzio" University of Chieti-Pescara, 66100, Chieti, Italy.
Laura AmodeiCenter for Advanced Studies and Technology (CAST), "G. d'Annunzio" University of Chieti-Pescara, 66100, Chieti, Italy.
Anna Giulia RuggieriCenter for Advanced Studies and Technology (CAST), "G. d'Annunzio" University of Chieti-Pescara, 66100, Chieti, Italy.
Francesca PotenzaCenter for Advanced Studies and Technology (CAST), "G. d'Annunzio" University of Chieti-Pescara, 66100, Chieti, Italy.
Marianna VieleCenter for Advanced Studies and Technology (CAST), "G. d'Annunzio" University of Chieti-Pescara, 66100, Chieti, Italy.
Manuela BombaCenter for Advanced Studies and Technology (CAST), "G. d'Annunzio" University of Chieti-Pescara, 66100, Chieti, Italy.
Francesco Del PizzoCenter for Advanced Studies and Technology (CAST), "G. d'Annunzio" University of Chieti-Pescara, 66100, Chieti, Italy.
Manuela IezziCenter for Advanced Studies and Technology (CAST), "G. d'Annunzio" University of Chieti-Pescara, 66100, Chieti, Italy.
Alberto GranzottoCenter for Advanced Studies and Technology (CAST), "G. d'Annunzio" University of Chieti-Pescara, 66100, Chieti, Italy.
Luca FedericiCenter for Advanced Studies and Technology (CAST), "G. d'Annunzio" University of Chieti-Pescara, 66100, Chieti, Italy.
Michele SalleseCenter for Advanced Studies and Technology (CAST), "G. d'Annunzio" University of Chieti-Pescara, 66100, Chieti, Italy. michele.sallese@unich.it.

Funding

PIANO NAZIONALE DI RIPRESA E RESILIENZA (PNRR) - Missione 6 - Componente 2 - Investimento 2.1 - "Valorizzazione e Potenziamento della Ricerca Biomedica del SSN" - Funded by European Union - NextGenerationEU PNRR-MR1-2022-12375730
6 · The paper itself

Abstract

Over the years, a diverse range of animal models has been established and employed in both basic and translational research, elucidating the intricate molecular mechanisms that drive cerebellar ataxias. However, many preclinical models remain insufficiently characterised, hindering our understanding of the diseases and the development of effective therapeutic approaches. The present study provides a comprehensive phenotypic and molecular characterisation of the woozy (Sil1

Indexed as

Cerebellar AtaxiaAnimalsDisease Models, AnimalDisease ProgressionFemaleMaleMiceMuscle, SkeletalPhenotypeSpinocerebellar DegenerationsBrain functional disturbancesCoordination impairmentsRare genetic disordersSex-related differences

Identifiers

PMID41350949
PMCPMC12680694

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.