ReviewHarm reduction journal2025
Practical guidance for navigating buprenorphine discontinuation.
Review in Harm reduction journal, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
0 citing papers in PubMed.
No citing paper in PubMed yet.
Corrections and comments
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Authors and funding
3 authors.
Funding
Abstract
Approximately 4.8 million people in the United States had opioid use disorder in 2024, with more than one hundred thousand experiencing an overdose death. Despite the established benefits of buprenorphine on morbidity and mortality, many patients may express an interest in discontinuing their medications for various reasons, including stigma surrounding addiction. There are limited studies describing how to navigate buprenorphine discontinuation. This commentary provides a practical approach to navigating buprenorphine discontinuation, using two case studies. Ideally, clinicians will develop a deep understanding of the patient's substance use journey, allowing them to understand both the internal and external factors driving their decision. Through this understanding, a clinician can develop a plan based on their well-being, safety, and risk factors for return to use. It is vital to reinforce that buprenorphine is a life-saving medication, can be continued life-long, and is a tool for recovery, not a barrier.
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Registered trials
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