Evidence map›Paper›PMID 41350760›Full record

ArticleInternational journal of legal medicine2026

Prevalence of directional asymmetry within the acetabulum and its implications for age estimation.

Varsha Warrier, Marta San-Millán, Tanuj Kanchan

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Article in International journal of legal medicine, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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4 · The record

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5 · Who and what money

Authors and funding

3 authors.

Varsha WarrierSchool of Sciences, College of Science and Engineering, University of Derby, Derby, UK.ORCID http://orcid.org/0000-0002-4874-5090
Marta San-MillánMedical Sciences Department, Clinical Anatomy, Embryology and Neuroscience Research Group (NEOMA), Faculty of Medicine, University of Girona, Girona, Spain. m.sanmillan@udg.edu.ORCID http://orcid.org/0000-0003-4165-429X
Tanuj KanchanDepartment of Forensic Medicine and Toxicology, All India Institute of Medical Sciences, Jodhpur, India.ORCID http://orcid.org/0000-0003-0346-1075

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Age estimation is a prerequisite for human identification. Within the skeletal framework, pelvic acetabular variables constitute a promising age marker. Previous investigations with the coxal bone have utilised either acetabulum for age estimation whilst assuming bilateral symmetry or selective side standardised practices, with two published studies reporting significant bilateral asymmetry within acetabular variables. The present study delves into this aspect of bilateral asymmetry further, and explores the prevalence, and impact of these side differences on age estimation. Data for analysis was obtained from 463 CT scans (195 females, 268 males) collected ethically from a medical institute in India previously. These scans were scored using a CT-based modification of the SanMillán-Rissech acetabular age estimation method, which utilises only the first five slightly modified variables of the original method as opposed to all seven. Collected data was then statistically analysed to illustrate the prevalence of asymmetry. The Wilcoxon test, Chi-square tests, mean % directional asymmetry values and equivalency ratios were utilised to assess population level lateralisation within the acetabulum. Furthermore, the association between asymmetry/ directionality, and biological sex and chronological age was investigated, and the impact of asymmetry on age estimation was evaluated using Bayesian regression analysis. Statistically significant bilateral differences were observed with the acetabular groove in females and the apex activity in males, and for all five variables the left acetabulum garnered older/ higher scores. Males largely demonstrated a greater degree of directionality wherein one side scored higher than the other more often, and patterns of directionality were seen to mostly increase with age in both sexes. The right, and/or younger scoring acetabulum consistently garnered most accurate age estimates, contradicting previous standardised practices of using the left acetabulum more, leading to its selective utilisation. Further, in-depth, investigation is wanting with regards to anatomical factors and lived experience of individuals capable of rationalizing these findings.

Indexed as

AcetabulumAge Determination by SkeletonAdolescentAdultAgedAged, 80 and overBayes TheoremFemaleForensic AnthropologyHumansIndiaMaleMiddle AgedTomography, X-Ray ComputedYoung AdultAcetabulumBayesian regressionDirectional asymmetryForensic age estimationHuman identification

Identifiers

PMID41350760
PMCPMC12957042

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.