ArticleNature neuroscience2026
The striatal indirect pathway mediates hesitation.
Article in Nature neuroscience, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
1 citing paper in PubMed.
- Shared striatal neurons exhibit context-specific dynamics for internally and externally driven actions.Science advances · 2026Article
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Authors and funding
3 authors.
Funding
Abstract
Hesitation-that is, pausing an action in the face of uncertainty-is ubiquitous in daily life, yet little is known about its underlying neural circuitry. We present a new experimental paradigm that reliably evokes hesitation in mice and find that hesitation is mediated by indirect, but not direct, pathway neurons in the dorsomedial striatum. These data establish a new role for the indirect pathway in suppressing action under uncertainty.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.