ReviewNature reviews. Nephrology2026
The global epidemiology of acute kidney injury: challenges and opportunities.
Review in Nature reviews. Nephrology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to 2 registered trials, which are not on this map. Cited by 25 papers, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Risk Stratification and Proactive Nursing Intervention for Acute Kidney Injury Following Interventional Therapy in Patients With Liver Cancer
Venous Return Pressure Gradient Predicts Acute Kidney Injury Onset and Progression
Who cites it
25 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Diagnostic and prognostic value of fibroblast growth factor 23 in acute kidney injury: systematic review and meta-analysis.Renal failure · 2026Pooled it
- Advances and perspectives of functional nanomaterials in scavenging reactive oxygen species for acute kidney injury.Bioactive materials · 2026Review
- Finerenone attenuates chronic fibrotic remodeling during the AKI-CKD transition in an ischemia-reperfusion-induced acute kidney injury mouse model.Renal failure · 2026Article
- Urinary UDP-sugars provide actionable prediction of acute kidney injury in cardiac surgery patients.American journal of physiology. Heart and circulatory physiology · 2026Article
- Review
- Prediction of Acute Kidney Injury in Oncology: From Clinical Risk Scores to AI-Enabled Precision Onco-Nephrology.Cancers · 2026Review
- Klotho-Derived Peptide 1 Protects against Acute Kidney Injury by Directly Targeting Mitochondrial ATAD3A.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2026Article
- Incidence, time trends and predictors of acute kidney injury in the region of Stockholm, Sweden.Scientific reports · 2026Article
- [Protective effects and underlying mechanisms of bone marrow mesenchymal stem cells-derived apoptotic extracellular vesicles in acute kidney injury].Zhongguo xiu fu chong jian wai ke za zhi = Zhongguo xiufu chongjian waike zazhi = Chinese journal of reparative and reconstructive surgery · 2026Article
- Down-Regulation of TFEB With Defective Autophagy in the Susceptibility of Aging Kidneys to Septic Acute Kidney Injury.Aging cell · 2026Article
- Novel nomogram for predicting acute kidney injury after cardiac surgery.Journal of thoracic disease · 2026Article
- Prognostic Nutritional Index as a Predictor of 90-Day Mortality in Surgical Sepsis Patients with Acute Kidney Injury-A Retrospective Cohort Study Based on the MIMIC-IV Database.Journal of clinical medicine · 2026Article
- DCBM-Tri: a dual-channel bilinear mapping triplet model for early recognition of acute kidney injury in imbalanced cohorts.Scientific reports · 2026Article
- Stress-Dependent NF-κB Signaling in Acute Kidney Injury: Linking Inflammation, Autophagy, and Apoptosis.International journal of molecular sciences · 2026Review
- Transition from acute kidney injury to chronic kidney disease: molecular mechanisms and therapeutic interventions.Molecular biomedicine · 2026Review
- Sodium bicarbonate therapy for metabolic acidosis in children stratified by acute kidney injury status and chloride levels: a retrospective cohort study.Translational pediatrics · 2026Article
- Plant-Based Proteins and Renal Protection in Acute Kidney Injury: Nutritional and Metabolic Perspectives.Nutrients · 2026Review
- Dual Roles and Therapeutic Prospects of Proximal Tubular Epithelial Cell Senescence in Acute Kidney Injury.Biomolecules · 2026Review
- Therapeutic rewiring of ceRNA networks: a computational pipeline for drug repurposing in acute kidney injury via circRNA-miRNA-mRNA axis disruption.Human genomics · 2026Review
- Mitochondrial dysfunction in sepsis-associated acute kidney injury: mechanisms and therapeutic potential.Frontiers in immunology · 2026Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
15 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Acute kidney injury (AKI) is a devastating complication of acute illness that affects adults and children across multiple settings worldwide and is associated with the development and progression of chronic kidney disease, increased mortality and increased resource utilization. Over the past two decades, standardization of criteria for AKI diagnosis and staging and the publication of multicentre studies have led to improved understanding of the AKI spectrum and provided insights into the heterogeneity of patient characteristics, processes of care and the environmental and sociodemographic factors that influence care delivery and outcomes. Substantial advances have been made in the utilization of electronic health records, biomarkers and care bundles - structured sets of evidence-based treatment practices - to improve the clinical management of AKI. The emerging fields of artificial intelligence and digital health may also provide ways to reduce the burden of this disease. However, these developments have occurred mainly in high-income countries and have yet to improve care delivery or outcomes in low-resource regions. Progress in the development of specific treatments for AKI is limited, and important gaps in knowledge and clinical practice remain, particularly in relation to the 5R framework (risk, recognition, response, renal support and rehabilitation) for managing AKI. An urgent need exists to address the wide variation and inequities in AKI management worldwide.
Indexed as
Identifiers
41350436What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.