Evidence map›Paper›PMID 41350431›Full record

ArticleCommunications chemistry2025

Conformational plasticity enables functional switching in diatom light-harvesting complexes.

Theofani-Iosifina Sousani, Boutheina Zender, Sayan Maity, Ulrich Kleinekathöfer, Vangelis Daskalakis

Abstract read
In one paragraph

Article in Communications chemistry, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Spectroscopic Investigation of the In Vivo Light-Dependent Photodynamics of the Marine Diatom Phaeodactylum tricornutum.Chemphyschem : a European journal of chemical physics and physical chemistry · 2026
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Theofani-Iosifina Sousani *Department of Chemical Engineering, University of Patras, Patras, Greece.
Boutheina Zender *Department of Chemical Engineering, University of Patras, Patras, Greece.ORCID http://orcid.org/0009-0005-4014-1726
Sayan MaitySchool of Science, Constructor University Bremen, Bremen, Germany.ORCID http://orcid.org/0000-0002-8758-594X
Ulrich KleinekathöferSchool of Science, Constructor University Bremen, Bremen, Germany.ORCID http://orcid.org/0000-0002-6114-7431
Vangelis DaskalakisDepartment of Chemical Engineering, University of Patras, Patras, Greece. vdaskalakis@upatras.gr.ORCID http://orcid.org/0000-0001-8870-0850

Funding

Deutsche Forschungsgemeinschaft (German Research Foundation) INST 676/7-1 FUGGEC | Horizon 2020 Framework Programme (EU Framework Programme for Research and Innovation H2020) 101119442
6 · The paper itself

Abstract

Biomolecules exhibit a fundamental correlation between structure and function, which can be modulated by environmental factors. Deciphering this relationship remains a central and long-standing challenge for many protein families. In this study, we investigate such a correlation in the light-harvesting complexes (LHCs) of diatoms; unicellular, photosynthetic organisms that thrive in marine ecosystems. Using μs-long molecular dynamics simulations and machine learning, we reveal that all experimentally resolved LHC configurations correspond to a few distinct interconverting states linked to an intrinsic conformational transition that might affect the balance between light-harvesting and photoprotective modes; a property that can be tuned or engineered. Thus, to the best of our knowledge, we provide an original view on the plethora of experimentally resolved structures. Our model strongly correlates with experimental findings on the effect of the photoprotective protein LHCX1 and the xanthophyll cycle on the FCP acclimation states.

Identifiers

PMID41350431
PMCPMC12680713

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.