ArticleScientific reports2025
Light-emitting diode red light attenuates epidermal thickening and keratinocyte proliferation in psoriasis models.
Article in Scientific reports, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
1 citing paper in PubMed.
- Multidimensional Regulatory Mechanisms and Targeted Therapeutic Strategies for Inhibited Keratinocyte Proliferation in Diabetic Wounds.Drug design, development and therapy · 2026Review
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Authors and funding
9 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Psoriasis is an immune-mediated skin condition that impacts approximately 3% of the United States population, with limited adjunctive therapy options. This study investigates the effects of light emitting diode red light (LED-RL) as a potential adjunct. Using in vitro keratinocytes, three-dimensional (3D) recapitulated skin models, and a mouse model, LED-RL's impact on keratinocyte proliferation and epidermal thickness was assessed. Our findings show that LED-RL significantly reduced keratinocyte proliferation without inducing apoptosis, likely through cell cycle modulation and decreased phosphorylation of STAT3, a pathway critical to psoriasis pathogenesis. In the 3D skin models, LED-RL at a dose of 640 J/cm
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