In one paragraphArticle in Nature communications, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
2 · The registryThe trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
3 · Its place in the literatureWho cites it
0 citing papers in PubMed.
No citing paper in PubMed yet.
4 · The recordCorrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
5 · Who and what moneyAuthors and funding
10 authors.
Yizhen QuanDepartment of Pharmacology, Vanderbilt Brain Institute, Vanderbilt Center for Addiction Research, Vanderbilt University, Nashville, TN, USA.
Justin D KimDepartment of Pharmacology, Vanderbilt Brain Institute, Vanderbilt Center for Addiction Research, Vanderbilt University, Nashville, TN, USA.
Janice J LeeDepartment of Pharmacology, Vanderbilt Brain Institute, Vanderbilt Center for Addiction Research, Vanderbilt University, Nashville, TN, USA.
Katherine N Gibson-CorleyDivision of Comparative Medicine, Department of Pathology, Microbiology, and Immunology, Vanderbilt University Medical Center, Nashville, TN, USA.ORCID http://orcid.org/0000-0002-1846-1580 Cody A SicilianoDepartment of Pharmacology, Vanderbilt Brain Institute, Vanderbilt Center for Addiction Research, Vanderbilt University, Nashville, TN, USA. cody.siciliano@vanderbilt.edu.ORCID http://orcid.org/0000-0001-9871-2089 Funding
Tumor Immunology and Microenvironment Research ProgramP30CA068485 · NCI · VANDERBILT UNIVERSITY MEDICAL CENTER · PI Ben Ho Park · 1995 to 2026
$172.8MOverall: Eunice Kennedy Shriver Intellectual and Developmental Disabilities Research Center at VanderbiltP50HD103537 · NICHD · VANDERBILT UNIVERSITY MEDICAL CENTER · PI Jeffrey L Neul · 2020 to 2026
$10.3MVAREC Research CoreP60AA031124 · NIAAA · VANDERBILT UNIVERSITY · PI Danny G. Winder · 2024 to 2026
$7.1MMesocortical neuromodulation in punishment-resistant alcohol drinkingR01AA030115 · NIAAA · VANDERBILT UNIVERSITY · PI Cody Siciliano · 2022 to 2026
$2.1M8/8: INIA Stress and Chronic Alcohol Interactions: Cross-species plasticity signatures of alcohol and stressU01AA029971 · NIAAA · VANDERBILT UNIVERSITY · PI Cody Siciliano · 2022 to 2026
$2.0MDefining the role of cortical circuit dynamics in learning and addictionR00DA045103 · NIDA · VANDERBILT UNIVERSITY · PI SICILIANO, CODY · 2020 to 2022
$764kDefining the role of cortical circuit dynamics in learning and addictionK99DA045103 · NIDA · MASSACHUSETTS INSTITUTE OF TECHNOLOGY · PI SICILIANO, CODY · 2018 to 2019
$366kEstrogen receptor regulation of cocaine effects on dopamine terminalsF31DA056202 · NIDA · VANDERBILT UNIVERSITY · PI ERICKSON, KIRSTY R. · 2022 to 2025
$149kRole of the kappa opioid receptor system in learning and substance use disordersF31DA056196 · NIDA · VANDERBILT UNIVERSITY · PI FARAHBAKHSH, ZAHRA · 2023 to 2024
$56kNCI NIH HHS P30 CA068485NIAAA NIH HHS P60 AA031124NIAAA NIH HHS R01 AA030115NIAAA NIH HHS U01 AA029971NICHD NIH HHS P50 HD103537NIDA NIH HHS F31 DA056196NIDA NIH HHS F31 DA056202NIDA NIH HHS K99 DA045103NIDA NIH HHS R00 DA045103U.S. Department of Health & Human Services | NIH | National Institute on Alcohol Abuse and Alcoholism (NIAAA) AA029971U.S. Department of Health & Human Services | NIH | National Institute on Alcohol Abuse and Alcoholism (NIAAA) AA030115U.S. Department of Health & Human Services | NIH | National Institute on Alcohol Abuse and Alcoholism (NIAAA) AA031124U.S. Department of Health & Human Services | NIH | National Institute on Drug Abuse (NIDA) DA045103U.S. Department of Health & Human Services | NIH | National Institute on Drug Abuse (NIDA) DA056196U.S. Department of Health & Human Services | NIH | National Institute on Drug Abuse (NIDA) DA056202
6 · The paper itselfAbstract
Intravenous drug self-administration has been widely used in behavioral neuroscience to model addiction and heightened motivational states; however, the technique is notoriously difficult and its utility has been in steady decline. Here, circumventing prior issues, we established a procedure for intranasal drug self-administration in head-restrained male mice. This procedure does not require surgical expertise or indwelling implants, drives robust schedule- and dose-dependent responding, and results in high blood cocaine concentrations. In addition to improved ease of use and face validity for modeling cocaine use disorder, this work provides an example of volitional nasal drug insufflation by a non-human animal, a behavior canonically thought to be unique to humans across compounds.
Indexed as
CocaineCocaine-Related DisordersSelf AdministrationAdministration, IntranasalAnimalsBehavior, AnimalDisease Models, AnimalDose-Response Relationship, DrugMaleMiceMice, Inbred C57BLCocaine
Identifiers
PMID41350263
PMCPMC12680761
What OpenQuestion holds
Textmetadata
LicenceCC BY
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