Evidence map›Paper›PMID 41349917›Full record

ArticleNeuropsychologia2026

MST in the wild: Optimizing the mnemonic similarity task for use in diverse environments.

Lilian Azer, Casey R Vanderlip, Lizabeth L Mayer, Luke Ehlert, David Sultzer, Hye-Won Shin, Craig E L Stark

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In one paragraph

Article in Neuropsychologia, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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0citing papers in PubMed
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1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

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Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Lilian AzerDepartment of Neurobiology & Behavior, University of California, Irvine, University of California Irvine, 1400 Biological Sciences III, Irvine, CA, 92697, USA. Electronic address: lazer@uci.edu.
Casey R VanderlipDepartment of Neurobiology & Behavior, University of California, Irvine, University of California Irvine, 1400 Biological Sciences III, Irvine, CA, 92697, USA.
Lizabeth L MayerDepartment of Neurobiology & Behavior, University of California, Irvine, University of California Irvine, 1400 Biological Sciences III, Irvine, CA, 92697, USA.
Luke EhlertDepartment of Neurobiology & Behavior, University of California, Irvine, University of California Irvine, 1400 Biological Sciences III, Irvine, CA, 92697, USA.
David SultzerInstitute for Memory Impairments and Neurological Disorders, University of California, Irvine, 2642 Biological Sciences III, Irvine, CA, 92697, USA; Department of Psychiatry & Human Behavior, UCI School of Medicine, 1001 Health Sciences Road, Irvine, CA, 92697, USA.
Hye-Won ShinInstitute for Memory Impairments and Neurological Disorders, University of California, Irvine, 2642 Biological Sciences III, Irvine, CA, 92697, USA; Somang Society, 5836 Corporate Ave., Ste 110, Cypress, CA, 90630, USA.
Craig E L StarkDepartment of Neurobiology & Behavior, University of California, Irvine, University of California Irvine, 1400 Biological Sciences III, Irvine, CA, 92697, USA; Institute for Memory Impairments and Neurological Disorders, University of California, Irvine, 2642 Biological Sciences III, Irvine, CA, 92697, USA; Somang Society, 5836 Corporate Ave., Ste 110, Cypress, CA, 90630, USA.

Funding

Development of the mnemonic similarity task as a tool to address age and dementia-related memory declineR01AG066683 · NIA · UNIVERSITY OF CALIFORNIA-IRVINE · PI STARK, CRAIG E · 2020 to 2024
$1.9M
Institute for Clinical and Translational Science NRSA Postdoctoral Research Training CoreT32TR005459 · NCATS · UNIVERSITY OF CALIFORNIA-IRVINE · PI VINCENT James CAIOZZO, Anand K Ganesan · 2025 to 2026
$340k
NCATS NIH HHS T32 TR005459NIA NIH HHS R01 AG066683
6 · The paper itself

Abstract

backgroundClear guidelines and tools for reliable measures of cognitive decline have yet to be established. This may be due to the absence of access to fully automated, self-administered, and scored cognitive screening tools.

methodsWe used the optimized Mnemonic Similarity Task (oMST; Stark et al., 2023), a web computer-based self-administered tool adapted from the MST. The oMST is designed for cognitive screening and population enrichment, offering a superior alternative to traditional neuropsychological tests. We tested the oMST's reliability, validity, and accessibility across five experiments with 1685 participants.

resultsLure discrimination was highly correlated between in-person and remote administration. These results were consistent across various testing sites, demonstrating the oMST's robustness. Importantly, visual acuity did not impact performance.

conclusionsOur findings establish the oMST as a reliable and accessible tool for cognitive screening across diverse testing environments and administration methods, addressing critical gaps in early screening for cognitive decline.

Indexed as

Cognitive DysfunctionNeuropsychological TestsAdultAgedAged, 80 and overFemaleHumansMaleMiddle AgedRecognition, PsychologyReproducibility of ResultsYoung AdultAgingAlzheimer’s diseaseAssessmentCognitionCognitive screening

Identifiers

PMID41349917
PMCPMC13203989

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LicenceCC BY
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.