Evidence map›Paper›PMID 41348959›Full record

ArticleEmerging microbes & infections2025

Chikungunya virus replicates in the human testis

Matéo Cartron, Vincent Ciesielski, Laurent Houzet, Krishani Dinali Perera, Hervé Abiven, María José Lista Brotos, Ingrid Plotton, Romain Mathieu, Julien Branchereau, Laurent Martin-Lefevre and 3 more

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Emerging microbes & infections, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors.

Matéo CartronInstitut National de la Santé et de la Recherche Médicale, Ecole des Hautes Etudes en Santé Publique, Institut de recherche en santé, environnement et travail, Université de Rennes - UMR_S1085, Rennes, France.ORCID 0009-0008-3256-4157
Vincent CiesielskiInstitut National de la Santé et de la Recherche Médicale, Ecole des Hautes Etudes en Santé Publique, Institut de recherche en santé, environnement et travail, Université de Rennes - UMR_S1085, Rennes, France.
Laurent HouzetInstitut National de la Santé et de la Recherche Médicale, Ecole des Hautes Etudes en Santé Publique, Institut de recherche en santé, environnement et travail, Université de Rennes - UMR_S1085, Rennes, France.
Krishani Dinali PereraInstitut National de la Santé et de la Recherche Médicale, Ecole des Hautes Etudes en Santé Publique, Institut de recherche en santé, environnement et travail, Université de Rennes - UMR_S1085, Rennes, France.
Hervé AbivenInstitut National de la Santé et de la Recherche Médicale, Ecole des Hautes Etudes en Santé Publique, Institut de recherche en santé, environnement et travail, Université de Rennes - UMR_S1085, Rennes, France.
María José Lista BrotosInstitut National de la Santé et de la Recherche Médicale, Ecole des Hautes Etudes en Santé Publique, Institut de recherche en santé, environnement et travail, Université de Rennes - UMR_S1085, Rennes, France.
Ingrid PlottonService de Médecine de la Reproduction, Hôpital Femme Mère Enfant, HCL, Bron, France.
Romain MathieuService d'Urologie, Centre Hospitalier Universitaire de Rennes, Rennes, France.
Julien BranchereauService d'Urologie, Centre Hospitalier Universitaire de Nantes, Nantes, France.
Laurent Martin-LefevreService de coordination des prélèvements, Centre Hospitalier Universitaire de Nantes, Nantes, France.
Pierre RoquesCenter for Immunology of Viral, Auto-Immune, Hematological and Viral Diseases (IMVA-HB/IDMIT), UMR-1184, Université Paris-Saclay, Inserm, CEA, Fontenay aux Roses, France.
Dominique MahéInstitut National de la Santé et de la Recherche Médicale, Ecole des Hautes Etudes en Santé Publique, Institut de recherche en santé, environnement et travail, Université de Rennes - UMR_S1085, Rennes, France.
Nathalie Dejucq-RainsfordInstitut National de la Santé et de la Recherche Médicale, Ecole des Hautes Etudes en Santé Publique, Institut de recherche en santé, environnement et travail, Université de Rennes - UMR_S1085, Rennes, France.ORCID 0000-0002-1788-2690

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Chikungunya virus (CHIKV) is an emerging, mosquito-borne alphavirus responsible for debilitating, long-lasting arthralgia and myalgia. In light of recent findings of prolonged CHIKV RNA shedding in human semen and testicular tropism in animals infected with related alphaviruses, it is imperative to investigate CHIKV's capacity to infect the human testis, an established reservoir for arboviruses like Zika, and to delineate its implications for testicular function. Using an

Indexed as

Chikungunya FeverChikungunya virusTestisVirus ReplicationBiomarkersCytokinesHumansMaleSeminiferous TubulesBiomarkersCytokinesCHIKVex vivo modelhuman testissexual transmissiontestis functions

Identifiers

PMID41348959
PMCPMC12683761

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.