Evidence map›Paper›PMID 41348504›Full record

ArticleClinical journal of the American Society of Nephrology : CJASN2026

Conservative Kidney Management in the Middle East and North Africa: A Comparative Study of Conflict and Nonconflict Settings.

Akram Al-Makki, David Gunderman, Valerie Luyckx, Taha Hatab, Imed Helal, Mayssaa Hoteit, Rana Yamout, Ala Ali, Abdulhafid Shebani, Najib AbuOsba and 3 more

Abstract readComparative Study
In one paragraph

Article in Clinical journal of the American Society of Nephrology : CJASN, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors.

Akram Al-MakkiIndiana University Health Arnett, Lafayette, Indiana.ORCID 0000-0002-4510-8010
David GundermanIndiana University School of Medicine-WL, West Lafayette, Indiana.ORCID 0000-0003-4154-0911
Valerie LuyckxUniversity Children's Hospital, University of Zurich, Zurich, Switzerland.ORCID 0000-0001-7066-8135
Taha HatabHouston Methodist DeBakey Heart and Vascular Center, Houston, Texas.
Imed HelalDepartment of Nephrology and Internal Medicine, Charles Nicolle Hospital, Tunis, Tunisia.ORCID 0000-0001-6996-2775
Mayssaa HoteitDepartment of Internal Medicine, Bridgeport Hospital/Yale New Haven Health, Bridgeport, Connecticut.ORCID 0000-0003-0315-522
Rana YamoutDivision of Palliative care, Medicine Department, American University of Beirut, Beirut, Lebanon.ORCID 0000-0002-9739-2164
Ala AliMedical Department, Nephrology and Renal Transplantation Center, Baghdad, Iraq.ORCID 0000-0001-5538-6068
Abdulhafid ShebaniNephrology Department, Tripoli University Hospital, Tripoli, Libya.ORCID 0000-0003-3413-4472
Najib AbuOsbaDivision of Nephrology, University of Yemen, Sanaa, Yemen.
Mohamed H SayeghFaculty of Medicine, American University of Beirut, Beirut, Lebanon.ORCID 0000-0002-2847-588
Krishna AllamSchool of Medicine, University of Minnesota, Minneapolis, Minnesota.ORCID 0009-0005-6087-6383
Sahar H KoubarDivision of Nephrology and Hypertension, University of Minnesota, Minneapolis, Minnesota.ORCID 0000-0002-1943-9377

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Conflicts severely disrupt care for patients with kidney failure, often limiting access to dialysis. In these challenging settings, conservative kidney management (CKM) emerges as a compassionate alternative focused on quality of life and symptom relief. This study explores how conflict conditions shape nephrologists' perceptions and implementation of CKM across the Middle East and North Africa (MENA) region. A web-based survey was distributed across 17 Arabic-speaking MENA countries over 3 months in 2022. Responses were divided into two groups according to the country's conflict status. Of the 334 nephrologist respondents, 66 were practicing in conflict zones and 268 in nonconflict zones. Conflict zone respondents were more likely to work part-time and less likely to be female. Dialysis in conflict zones was more likely funded by charitable sources (odds ratio [OR], 4.22; 95% confidence interval [CI], 1.36 to 13.07). Compared with nonconflict zones, nephrologists in conflict areas reported significantly less access to palliative care (OR, 3.36; 95% CI, 1.3 to 8.68) and cited lack of CKM training and limited access to CKM programs as barriers to its implementation (OR, 2.59; 95% CI, 1.24 to 5.38 and OR, 3.42; 95% CI, 1.59 to 7.35; respectively). While overall awareness of CKM was similar, those in conflict zones expressed greater moral and religious discomfort with withholding dialysis. These findings underscore important ethical, operational, and access-related disparities in CKM delivery in conflict zones in the MENA region. Addressing these gaps through supportive ethical policies focusing on procedural and distributive justice, increased nephrologists' awareness and training, and enhanced efforts to strengthen palliative care services are essential tools for establishing CKM as a viable and ethical approach for patients in conflict-affected regions.

Indexed as

Armed ConflictsConservative TreatmentNephrologistsPractice Patterns, Physicians'Renal InsufficiencyAfrica, NorthernAttitude of Health PersonnelFemaleHealth Services AccessibilityHumansMaleMiddle EastPalliative CareRenal DialysisCKDCKD nondialysisconservative managementESKDethicspalliative caresupportive care

Identifiers

PMID41348504
PMCPMC13268373

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.