Evidence map›Paper›PMID 41348477›Full record

ArticleChemistry & biodiversity2026

Analysis of Phytochemicals and Functional Groups From Aqueous Extracts of Malawian Vernonia amygdalina Del. for Potential Applications.

Bonface Mwamatope, Elijah Malinga Menard Wanda, Ibrahim Chikowe, Naomi Chikwana, Fednand Paul Wanjala, Lesten Eliez Chisomo Chatepa, John Finias Kamanula

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Article in Chemistry & biodiversity, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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1 · What the graph read from it

What it found

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2 · The registry

The trial behind it

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3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

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PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Bonface MwamatopeBasic Science Department, Faculty of Agriculture, Lilongwe University of Agriculture and Natural Resources, Lilongwe, Malawi.ORCID https://orcid.org/0000-0001-7929-7844
Elijah Malinga Menard WandaAfrican Centre of Excellence in Neglected and Underutilised Biodiversity, Mzuzu, Malawi.ORCID https://orcid.org/0000-0002-0360-0939
Ibrahim ChikowePharmacy Department, Kamuzu University of Health Sciences, Blantyre, Malawi.ORCID https://orcid.org/0000-0002-8231-9140
Naomi ChikwanaBasic Science Department, Faculty of Agriculture, Lilongwe University of Agriculture and Natural Resources, Lilongwe, Malawi.
Fednand Paul WanjalaAfrican Centre of Excellence in Neglected and Underutilised Biodiversity, Mzuzu, Malawi.
Lesten Eliez Chisomo ChatepaBasic Science Department, Faculty of Agriculture, Lilongwe University of Agriculture and Natural Resources, Lilongwe, Malawi.
John Finias KamanulaAfrican Centre of Excellence in Neglected and Underutilised Biodiversity, Mzuzu, Malawi.ORCID https://orcid.org/0000-0003-3193-1759

Funding

The African Centre of Excellence in Neglected and Underutilized Biodiversity
6 · The paper itself

Abstract

Vernonia amygdalina Del., a plant recognised for its medicinal properties, is widely available in Malawi, but remains underutilised. The study aimed to analyse phytochemicals and their functional groups in the aqueous extracts of V. amygdalina Del. leaves. The functional groups of the compounds were determined using Fourier-transform infrared spectroscopy (FT-IR). Phenolic compounds were quantified using high-performance liquid chromatography-ultraviolet visible assay. Gas chromatography mass spectrometry was used to identify volatile phytoconstituents. The FT-IR spectrum revealed characteristic absorption bands corresponding to C═C, C═O, C═O, ─OH and ─NH active functional groups. The phenolic compounds identified included gallic acid, sinapic acid, vanillic acid, ferulic acid, rutin and quercetin, whose concentrations varied significantly (p < 0.05). Volatile compounds (21) were observed with dl-α-Tocopherol as a major compound, followed by β-sitosterol, ethyl iso-allocholate, 9,12,15-octadecatrienoic acid, 2,3-dihydroxypropyl ester, (Z,Z,Z)- and stigmasterol. The aqueous extracts of V. amygdalina Del. leaves contained phytochemicals with active functional groups that can act as reducing and capping agents, thereby demonstrating potential applications in green chemistry. Based on these findings, we recommend further studies using this extract to actually synthesise silver and zinc oxide nanoparticles and characterise them using spectroscopic techniques for use in promoting sustainable farming practices.

Indexed as

PhytochemicalsPlant ExtractsVernoniaChromatography, High Pressure LiquidGas Chromatography-Mass SpectrometryMalawiPhenolsPlant LeavesSpectroscopy, Fourier Transform InfraredWaterPhenolsPhytochemicalsPlant ExtractsWaterfunctional groupsgreen chemistryHPLC‐UV‐Visnanoparticles and phytochemicals

Identifiers

PMID41348477
PMCPMC13420621

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