Evidence map›Paper›PMID 41348318›Full record

Observational studySurgery today2026

Prevalence of and risk factors for low anterior resection syndrome based on the international consensus definition: a multicenter cross-sectional observational study.

Yosuke Atsumi, Masakatsu Numata, Koji Numata, Manabu Shiozawa, Keisuke Kazama, Sho Sawazaki, Atsuhiko Sugiyama, Hiroyuki Mushiake, Nobuhiro Sugano, Teni Godai and 7 more

Abstract readMulticenter StudyObservational Study
PubMed Publisher
In one paragraph

Observational study in Surgery today, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Observational
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

17 authors.

Yosuke AtsumiDepartment of Surgery, Gastroenterological Center, Yokohama City University Medical Center, 4-57 Urafune-cho, Minami-ku, Yokohama, 232-0024, Kanagawa, Japan.
Masakatsu NumataDepartment of Surgery, Gastroenterological Center, Yokohama City University Medical Center, 4-57 Urafune-cho, Minami-ku, Yokohama, 232-0024, Kanagawa, Japan. numata@yokohama-cu.ac.jp.ORCID http://orcid.org/0000-0003-0414-0046
Koji NumataDepartment of Colorectal Surgery, Kanagawa Cancer Center, Yokohama, Japan.
Manabu ShiozawaDepartment of Colorectal Surgery, Kanagawa Cancer Center, Yokohama, Japan.
Keisuke KazamaDepartment of Surgery, Yokohama City University, Yokohama, Japan.
Sho SawazakiDepartment of Surgery, Yokohama City University, Yokohama, Japan.
Atsuhiko SugiyamaDepartment of Surgery, Saiseikai Yokohamashi Nanbu Hospital, Yokohama, Japan.
Hiroyuki MushiakeDepartment of Surgery, Saiseikai Yokohamashi Nanbu Hospital, Yokohama, Japan.
Nobuhiro SuganoDepartment of Surgery, Hiratsuka Kyosai Hospital, Hiratsuka, Japan.
Teni GodaiDepartment of Surgery, Fujisawa Shonandai Hospital, Fujisawa, Japan.
Yusuke KatayamaDepartment of Surgery, Japanese Red Cross Hadano Hospital, Hadano, Japan.
Akio HiguchiDepartment of Surgery, Yokohama Minami Kyosai Hospital, Yokohama, Japan.
Mamoru UchiyamaDepartment of Surgery, Ashigara-kami Hospital, Ashigara, Japan.
Yo MikayamaDepartment of Surgery, Ashigara-kami Hospital, Ashigara, Japan.
Kentaro SaitoDepartment of Surgery, International University of Health and Welfare, Atami Hospital, Atami, Japan.
Takashi KomuraDepartment of Surgery, International University of Health and Welfare, Atami Hospital, Atami, Japan.
Aya SaitoDepartment of Surgery, Yokohama City University, Yokohama, Japan.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposesThe symptoms of low anterior resection syndrome (LARS) are diverse, and its ambiguous definition has made estimating its prevalence difficult. In 2018, an international consensus proposed a new LARS definition based on eight symptoms and consequences. We conducted this study to evaluate the prevalence of LARS, using this new definition (LARS-ND), and to identify its risk factors.

methodsThis multicenter, cross-sectional study surveyed patients who underwent curative resection for rectal tumors between 2020 and 2022 at 10 institutions. A one-time questionnaire based on the new LARS definition was distributed. Outcomes included LARS-ND prevalence and risk factors.

resultsA total of 343 patients responded (response rate: 86.6%). The prevalence of LARS-ND was 72.5%, with no significant differences across groups with different follow-up durations. The most frequent symptom and consequence were "emptying difficulties" (93.3%) and "the need for strategies and compromises" (47.5%). Among patients categorized as having "no LARS" by the conventional score, 25% were diagnosed with LARS-ND. Multivariate analysis identified younger age (< 70 years; OR = 2.28) and short anastomosis distance (≤ 5 cm; OR = 1.96) as risk factors.

conclusionsThe prevalence of LARS-ND was high, and the new LARS definition identified patients with symptoms previously missed by the conventional score. Younger age and a lower anastomosis level appear to be risk factors for LARS-ND.

Indexed as

Postoperative ComplicationsRectal NeoplasmsRectumAdultAgedAged, 80 and overAge FactorsAnastomosis, SurgicalConsensus Statements as TopicCross-Sectional StudiesFemaleHumansInternationalityLow Anterior Resection SyndromeMaleMiddle AgedBowel dysfunctionLow anterior resection syndrome (LARS)New LARS definitionQuality of life (QOL)Rectal cancerRisk factors

Identifiers

PMID41348318

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.