Evidence map›Paper›PMID 41348216›Full record

ArticleSupportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer2025

Trajectories of postoperative nutritional risk changes in patients with oesophageal cancer and their relationship with symptom recovery-a multicentre longitudinal study.

Shaoxue Li, Yanni Qin, Jing Chen, Anqi Miao, Shuwen Li

Abstract readMulticenter Study
PubMed Publisher
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Article in Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

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1citing papers in PubMed
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5 · Who and what money

Authors and funding

5 authors.

Shaoxue LiSchool of Nursing, Guangzhou Medical University, Guangzhou, Guangdong Province, China.
Yanni QinSchool of Nursing, Guangzhou Medical University, Guangzhou, Guangdong Province, China.
Jing ChenSchool of Nursing, Guangzhou Medical University, Guangzhou, Guangdong Province, China.
Anqi MiaoSchool of Nursing, Guangzhou Medical University, Guangzhou, Guangdong Province, China.
Shuwen LiSchool of Nursing, The First Affiliated Hospital, Anhui Medical University, Hefei, Anhui Province, China. lishuwen@ahmu.edu.cn.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeThis study aimed to chart the trajectory of predicted postoperative nutritional risk in patients with oesophageal cancer and to explore further the impact of patients' postoperative symptom burden on the nutritional risk trajectory.

methodThe nutritional risk of patients with oesophageal cancer was assessed using the geriatric nutritional risk index (GNRI), prognosis nutritional index (PNI), and lymphocyte count, and symptom burden was assessed using the Convalescent Symptom Assessment Scale for Oesophagectomy Patients. The trajectory of postoperative nutritional change in patients was depicted using unconditional free estimation Latent Growth Curve Model (LGCM), and factors influencing the trajectory of nutritional risk change and the effect of symptom burden on the trajectory of nutrition were explored using conditional LGCM.

resultsPostoperative nutritional risk of patients with oesophageal cancer generally declined 1-2 days after surgery. The GNRI declined by less than 10%, the PNI by more than 20%, and the change in lymphocyte counts dropped by more than 60%. Gender, residence, chronic diseases, healthcare payment methods, and chemotherapy were significant factors influencing patients' nutritional risk changes. Overall symptoms at 1-2 days postoperatively affect initial postoperative levels of PNI, overall and late symptoms affect initial postoperative levels of lymphocytes, while late and psychological symptoms affect the rate of lymphocyte recovery.

conclusionPostoperative days 1-2 are a critical period for nutritional risk in patients with oesophageal cancer, when symptom burden affects the trajectory of changes in nutritional risk. Medical personnel can improve the nutritional risk of patients by reducing the symptom burden.

Indexed as

Esophageal NeoplasmsEsophagectomyMalnutritionNutritional StatusPostoperative ComplicationsAgedAged, 80 and overFemaleHumansLongitudinal StudiesLymphocyte CountMaleMiddle AgedNutrition AssessmentPostoperative PeriodPrognosisElderly peopleNutritional indicatorsOesophageal cancerSymptom burden

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