Evidence map›Paper›PMID 41348154›Full record

ArticleBrain informatics2025

Boosting brain tumor detection with an optimized ResNet and explainability via Grad-CAM and LIME.

K Afnaan, C G Arunbalaji, Tripty Singh, Rishab Kumar, Ganesh R Naik

Abstract read
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Article in Brain informatics, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

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3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

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4 · The record

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5 · Who and what money

Authors and funding

5 authors.

K Afnaan *Department of Computer Science and Engineering, Amrita School of Computing, Amrita Vishwa Vidyapeetham, Bangalore, Karnataka, India.
C G Arunbalaji *Department of Computer Science and Engineering, Amrita School of Computing, Amrita Vishwa Vidyapeetham, Bangalore, Karnataka, India.
Tripty Singh *Department of Computer Science and Engineering, Amrita School of Computing, Amrita Vishwa Vidyapeetham, Bangalore, Karnataka, India. tripty_singh@blr.amrita.edu.
Rishab Kumar *Amrita School of Medicine, Amrita Vishwa Vidyapeetham, Faridabad, India.
Ganesh R Naik *Centre for Artificial Intelligence Research and Optimization (AIRO), Torrens University, Ultimo, NSW, 2007, Australia.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Detecting Brain Tumors is essential in medical imaging, as early and accurate diagnosis significantly improves treatment decisions and patient outcomes. Convolutional Neural Networks have demonstrated high efficiency in this domain, but their lack of interpretability remains a significant drawback for clinical adoption. This study explores the integration of Explainability techniques to enhance transparency in CNN-based classification and improve model performance through advanced optimization strategies. The primary research question addressed is how to improve the accuracy, generalization, and interpretability of CNNs for brain tumor Detection. While previous studies have demonstrated the effectiveness of deep learning for tumor detections, challenges such as class imbalance and overfitting of CNNs persist. To bridge this gap, we employ different dynamic learning rate modifiers, perform architectural enhancements, and apply XAI techniques, including Grad-CAM and LIME. Our experiments are conducted on three publicly available multiclass tumor datasets to ensure the generalizability of the proposed approach. Among the tested architectures, the enhanced ResNet model consistently outperformed others across all datasets, achieving the highest test accuracy, ranging from 99.36% to 99.65%. The techniques such as unfreezing layers, integrating various blocks, pooling, and dropout layers enhanced feature refinement and reduced overfitting. By incorporating XAI, we improve model interpretability, ensuring that clinically relevant regions in MRI scans are highlighted. These advancements contribute to highly reliable AI-assisted diagnostics, addressing significant challenges in medical image classification.

Indexed as

Brain tumor classificationConvolutional Neural Networks (CNN)Explainable AI (XAI)Grad-CAM

Identifiers

PMID41348154
PMCPMC12680819

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.