Evidence map›Paper›PMID 41348111›Full record

ArticleThe Journal of general virology2025

Genoprevalence of cutavirus in benign and malignant intestinal and breast tissues.

Irini M Assimakopoulou, Ushanandini Mohanraj, Taina Sipponen, Anna Lepistö, Dalia Y Kadry, Rana Hamdy, Mahmoud M Kamel, Heba M El-Batal, Ahmed S Abdel-Moneim, Maria Söderlund-Venermo

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Article in The Journal of general virology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Irini M AssimakopoulouDepartment of Virology, University of Helsinki, Helsinki, Finland.
Ushanandini MohanrajDepartment of Virology, University of Helsinki, Helsinki, Finland.
Taina SipponenGastroenterology, Abdominal Center, Helsinki University Hospital and University of Helsinki, Helsinki, Finland.
Anna LepistöDepartment of Surgery, Helsinki University Hospital, Helsinki, Finland.
Dalia Y KadryClinical Pathology Department, National Cancer Institute, Cairo University, Cairo, Egypt.
Rana HamdyPediatric Oncology Department, National Cancer Institute, Cairo University, Cairo, Egypt.
Mahmoud M KamelClinical Pathology Department, National Cancer Institute, Cairo University, Cairo, Egypt.
Heba M El-BatalDepartment of Medical Microbiology & Immunology, Cairo University, Giza, Egypt.
Ahmed S Abdel-MoneimDepartment of Microbiology and Immunology, College of Medicine and Health Sciences, Sultan Qaboos University, Muscat, Oman.
Maria Söderlund-VenermoDepartment of Virology, University of Helsinki, Helsinki, Finland.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Cutavirus (CuV), the newest human protoparvovirus (PPV), has gained attention due to its significant association with cutaneous T-cell lymphoma (CTCL) and its precursor, parapsoriasis, whereas the other human PPVs, bufavirus and tusavirus, show no such link. Given this association, it is important to investigate the prevalence of CuV DNA in other tissues, particularly those affected by malignancy or inflammation. This study assessed, by multiplex quantitative PCR, the genoprevalences of all three PPVs in 427 fresh-frozen intestinal biopsies from inflammatory bowel disease (IBD), colorectal cancer, adenomas or healthy mucosa of 185 individuals, as well as in 94 formalin-fixed paraffin-embedded (FFPE) biopsies from malignant and non-malignant breast conditions of 85 patients. The study also compared the DNA prevalences of human herpesvirus (HHV)-6A, -6B and -7 in the breast tissues. CuV mRNA was assayed with reverse-transcription PCR, and corresponding FFPE sections underwent

Indexed as

BreastBreast NeoplasmsIntestinesParvoviridae InfectionsParvovirusAdultAgedAged, 80 and overDNA, ViralFemaleHerpesvirus 6, HumanHerpesvirus 7, HumanHumansInflammatory Bowel DiseasesMaleMiddle AgedDNA, Viralbreast cancercolorectal cancercutavirus (CuV)human herpesviruses (HHV-6B, HHV-6A, HHV-7)inflammatory bowel disease (IBD)parvovirus

Identifiers

PMID41348111
PMCPMC12680079

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.