Evidence map›Paper›PMID 41347870›Full record

ArticleExperimental physiology2026

Corticospinal, reticulospinal and motoneuronal contributions to fatigability during a sustained contraction of the elbow flexors.

Oliver Hayman, Rosiered Brownson-Smith, Elliott I Atkinson, Padraig Spillane, Stuart Baker, Stuart Goodall, Glyn Howatson, Kevin Thomas, Paul Ansdell

Abstract read
In one paragraph

Article in Experimental physiology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Review
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Oliver HaymanDepartment of Sport, Exercise and Rehabilitation, Faculty of Health and Life Sciences, Northumbria University, Newcastle upon Tyne, UK.ORCID https://orcid.org/0000-0003-2100-0029
Rosiered Brownson-SmithDepartment of Sport, Exercise and Rehabilitation, Faculty of Health and Life Sciences, Northumbria University, Newcastle upon Tyne, UK.
Elliott I AtkinsonDepartment of Sport, Exercise and Rehabilitation, Faculty of Health and Life Sciences, Northumbria University, Newcastle upon Tyne, UK.ORCID https://orcid.org/0000-0003-4884-1135
Padraig SpillaneDepartment of Sport, Exercise and Rehabilitation, Faculty of Health and Life Sciences, Northumbria University, Newcastle upon Tyne, UK.
Stuart BakerMedical School, Newcastle University, Newcastle upon Tyne, UK.
Stuart GoodallDepartment of Sport, Exercise and Rehabilitation, Faculty of Health and Life Sciences, Northumbria University, Newcastle upon Tyne, UK.ORCID https://orcid.org/0000-0001-9029-2171
Glyn HowatsonDepartment of Sport, Exercise and Rehabilitation, Faculty of Health and Life Sciences, Northumbria University, Newcastle upon Tyne, UK.ORCID https://orcid.org/0000-0001-8494-2043
Kevin ThomasDepartment of Sport, Exercise and Rehabilitation, Faculty of Health and Life Sciences, Northumbria University, Newcastle upon Tyne, UK.ORCID https://orcid.org/0000-0003-2973-5337
Paul AnsdellDepartment of Sport, Exercise and Rehabilitation, Faculty of Health and Life Sciences, Northumbria University, Newcastle upon Tyne, UK.ORCID https://orcid.org/0000-0001-7542-1107

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Synaptic input to the motoneuron pool is altered during fatiguing muscle contractions. In humans, the corticospinal tract is often studied, with equivocal findings regarding its role in the reduction of force. To date, the involvement of the reticulospinal tract during states of fatigue has not been explored. Fourteen participants (28 ± 6 years, nine males) visited the laboratory twice, first for a familiarisation, then for an experimental trial. Participants completed a 5-min sustained elbow flexor contraction at an intensity eliciting 40% of the EMG recorded during a maximal isometric voluntary contraction (MVC). Before, during and after the contraction, transcranial magnetic stimulation and electrical cervicomedullary stimulation were used to elicit motor evoked potentials (MEPs) and cervicomedullary evoked potentials during the silent period (SP-CMEPs), respectively, with CMEPs also being evoked in combination with a startling acoustic sound (CMEPcon). Electrical stimulation of the brachial plexus was used to evoke maximal compound action potentials of the elbow flexors (M

Indexed as

ElbowMotor NeuronsMuscle ContractionMuscle FatigueMuscle, SkeletalPyramidal TractsAdultBrachial PlexusElectric StimulationElectromyographyEvoked Potentials, MotorFemaleHumansIsometric ContractionMaleTranscranial Magnetic Stimulationcentraldescending tractexercisefatigueneuralneuromuscular

Identifiers

PMID41347870
PMCPMC13140560

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.