Evidence map›Paper›PMID 41347605›Full record

ArticleJournal of cosmetic dermatology2025

Effect of a Dihydroxyacetone-Based Camouflage Agent on Ultraviolet-Induced Erythema.

Dan Shu, Yiting Han, Dian Chen, Zhenghui Li, Yi Zhao

Abstract read
In one paragraph

Article in Journal of cosmetic dermatology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Dan ShuDepartment of Dermatology, Beijing Tsinghua Changgung Hospital, Tsinghua University, Beijing, P.R. China.
Yiting HanDepartment of Dermatology, Beijing Tsinghua Changgung Hospital, Tsinghua University, Beijing, P.R. China.
Dian ChenDepartment of Dermatology, Beijing Tsinghua Changgung Hospital, Tsinghua University, Beijing, P.R. China.
Zhenghui LiDepartment of Dermatology, Beijing Tsinghua Changgung Hospital, Tsinghua University, Beijing, P.R. China.
Yi ZhaoDepartment of Dermatology, Beijing Tsinghua Changgung Hospital, Tsinghua University, Beijing, P.R. China.ORCID https://orcid.org/0000-0002-4531-8632

Funding

Beijing Hospitals Authority's Ascent Plan DFL20240901National Key Research and Development Program of China 2023YFC2508100
6 · The paper itself

Abstract

backgroundVitiligo is an acquired, idiopathic skin disease of dyspigmentation, affecting approximately 0.5%-2% of the global population. However, it is not clear whether dihydroxyacetone (DHA)-based camouflage could affect the effectiveness of ultraviolet (UV) therapy. Therefore, we aimed to investigate the effect of a camouflage agent containing 3.6% DHA on UV-induced erythema.

methodsFifty-one healthy volunteers of skin type III to IV who came to the hospital were recruited in this study. A 308 nm excimer UV lamp was used to perform the minimum erythema dose (MED) test on the lower back and a camouflage agent containing 3.6% DHA was applied. Four groups were tested on the same individuals (subjects served as their own controls), including no camouflage nor irradiation (Group A), irradiation without camouflage (Group B), camouflage without irradiation (Group C), and camouflage plus irradiation (Group D). Refined MED was evaluated via naked eyes (erMED) and digital dermatoscopes (drMED), The erythema index (EI) value of the targeted site was measured by dermatoscopic digital imaging and analyzed.

resultsAfter the camouflage masking, 43 (84.3%) subjects remained unchanged in erMED, 7 (13.7%) had a MED increase of one grade (+10 mJ/cm

conclusionThe camouflage agent containing 3.6% DHA exhibits statistically significant but clinically negligible effects on erythema in volunteers exposed to 308 nm UV light, requiring no dose adjustment in 84.3% of cases.

Indexed as

DihydroxyacetoneErythemaUltraviolet RaysUltraviolet TherapyVitiligoAdultDermoscopyFemaleHealthy VolunteersHumansMaleMiddle AgedSkinYoung AdultDihydroxyacetonecamouflagedihydroxyacetoneerythemaultraviolet

Identifiers

PMID41347605
PMCPMC12679678

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.