Evidence map›Paper›PMID 41347555›Full record

ArticleClinical cardiology2025

Underestimation of Stent Efficacy: Untreated Artery Events Distort Coronary Intervention Outcomes.

Mauricio Rigodanzo Mocha, Whady Hueb, Paulo Cury Rezende, Matheus de Oliveira Laterza Ribeiro, Thiago Luis Scudeler, Eduardo Gomes Lima, José Antonio Franchini Ramires, Roberto Kalil Filho

Abstract read
In one paragraph

Article in Clinical cardiology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Mauricio Rigodanzo MochaDivisão Clinica, Instituto do Coracao, Hospital das Clinicas HCFMUSP, Faculdade de Medicina, Universidade de São Paulo, Sao Paulo, BR.ORCID https://orcid.org/0000-0001-8994-2771
Whady HuebDivisão Clinica, Instituto do Coracao, Hospital das Clinicas HCFMUSP, Faculdade de Medicina, Universidade de São Paulo, Sao Paulo, BR.
Paulo Cury RezendeDivisão Clinica, Instituto do Coracao, Hospital das Clinicas HCFMUSP, Faculdade de Medicina, Universidade de São Paulo, Sao Paulo, BR.ORCID https://orcid.org/0000-0001-8625-1537
Matheus de Oliveira Laterza RibeiroDivisão Clinica, Instituto do Coracao, Hospital das Clinicas HCFMUSP, Faculdade de Medicina, Universidade de São Paulo, Sao Paulo, BR.
Thiago Luis ScudelerDivisão Clinica, Instituto do Coracao, Hospital das Clinicas HCFMUSP, Faculdade de Medicina, Universidade de São Paulo, Sao Paulo, BR.
Eduardo Gomes LimaDivisão Clinica, Instituto do Coracao, Hospital das Clinicas HCFMUSP, Faculdade de Medicina, Universidade de São Paulo, Sao Paulo, BR.
José Antonio Franchini RamiresDivisão Clinica, Instituto do Coracao, Hospital das Clinicas HCFMUSP, Faculdade de Medicina, Universidade de São Paulo, Sao Paulo, BR.
Roberto Kalil FilhoDivisão Clinica, Instituto do Coracao, Hospital das Clinicas HCFMUSP, Faculdade de Medicina, Universidade de São Paulo, Sao Paulo, BR.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundEvaluation of percutaneous coronary intervention (PCI) effectiveness typically focuses on overall coronary events, often overlooking the specific location of these events within the coronary vasculature. This study aimed to evaluate the incidence of coronary events in patients treated with PCI and to investigate the correlation between these events, the location of the event within the treated site, and the type of stent used.

methodsThis study determined the proportion of coronary events occurring after percutaneous coronary intervention (PCI) and investigated the association between these events and the location of the previous treatment site. A retrospective cohort analysis was conducted on patients with stable coronary artery disease (CAD) who underwent PCI using either conventional or drug-eluting stents. Data was obtained from the MASS Clinical Research Unit database. The location of the coronary event was determined by angiography.

resultsFive hundred and sixty two patients were included, with 232 (41.3%) experiencing coronary events. 55.8% of the events occurred at the treated site, while the remaining 44.2% were unrelated to the treated site. Of the events related to the treated site, 54.1% occurred in the conventional stent group and 61.1% in the drug-eluting stent group. No statistically significant association was found between the event in the treated site and the type of stent used (p = 0.363).

conclusionsA significant proportion of coronary events occurred in untreated sites. Our results suggest that isolated evaluation of the treated site may provide a more accurate estimate of the effectiveness of stents.

Indexed as

Coronary Artery DiseaseCoronary VesselsDrug-Eluting StentsPercutaneous Coronary InterventionStentsAgedCoronary AngiographyFemaleHumansIncidenceMaleMiddle AgedProsthesis DesignRetrospective StudiesRisk FactorsTreatment Outcomeangioplastycardiovascular eventspercutaneous coronary interventionstable coronary artery disease

Identifiers

PMID41347555
PMCPMC12679305

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.