Evidence map›Paper›PMID 41347496›Full record

ReviewMycoses2025

The Importance of Early Mycological Clearance of Uncomplicated Candidaemia and Its Implications for Clinical Practice.

O A Cornely, M Bassetti, C Garcia-Vidal, M Hoenigl, J Maertens, I Martin-Loeches, J P Mira, P L White

Abstract readReview
In one paragraph

Review in Mycoses, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

O A CornelyGerman Centre for Infection Research (DZIF), Partner Site Bonn-Cologne, Cologne, Germany.ORCID https://orcid.org/0000-0001-9599-3137
M BassettiInfectious Diseases Unit, Policlinico San Martino Hospital, IRCCS, Genoa, Italy.
C Garcia-VidalDepartment of Infectious Diseases, Hospital Clinic of Barcelona-IDIBAPS, University of Barcelona, Barcelona, Spain.
M HoeniglDivision of Infectious Diseases, Translational Medical Mycology Research Unit, European Confederation of Medical Mycology Excellence Center for Medical Mycology, Medical University of Graz, Graz, Austria.ORCID https://orcid.org/0000-0002-1653-2824
J MaertensDepartment of Microbiology, Immunology and Transplantation, KU Leuven, Leuven, Belgium.ORCID https://orcid.org/0000-0003-4257-5980
I Martin-LoechesDepartment of Intensive Care Medicine, Multidisciplinary Intensive Care Research Organisation (MICRO), St James's Hospital, Dublin, Ireland.
J P MiraService de Médecine Intensive and Réanimation, Hôpital Cochin, Assistance Publique-Hôpitaux de Paris, Institut Cochin, Université Paris Cité, Paris, France.
P L WhitePublic Health Wales Mycology Reference Laboratory, University Hospital of Wales, Cardiff, UK.

Funding

Mundipharma Research Limited
6 · The paper itself

Abstract

Invasive candidiasis is a life-threatening infection associated with high morbidity, mortality and healthcare costs in both general and critical care settings. Timely diagnosis and adequate antifungal treatment are essential to improving patient outcomes and limiting unnecessary use of healthcare resources. This review explores the relationship between early Candida clearance with antifungal therapy, clinical outcomes, resistance patterns and economic impact. It also evaluates the role of diagnostic markers in facilitating early and accurate identification of candidaemia, enabling more precise and effective clinical management. Special attention is given to the challenges of managing candidaemia in critically ill and neutropenic patients, highlighting the need for tailored and timely interventions in these vulnerable populations.

Indexed as

Antifungal AgentsCandidaCandidemiaCritical IllnessDrug Resistance, FungalHumansTreatment OutcomeAntifungal Agentsantifungal agentscandidaemiaPCRsystemic infection

Identifiers

PMID41347496
PMCPMC12679526

What OpenQuestion holds

Textmetadata
LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.