Evidence map›Paper›PMID 41347271›Full record

ArticleJournal of pediatric gastroenterology and nutrition2026

Hepatopulmonary syndrome in children and adolescents with portal hypertension in Brazil: A multicenter study.

Leticia Drumond Alberto, Eleonora Druve Tavares Fagundes, Adriana Teixeira Rodrigues, Thaís Costa Nascentes Queiroz, Gustavo Valverde de Castro, Carlos Oscar Kieling, Sandra Maria Gonçalves Vieira, Natália Lamounier Dos Martires Guerra, Natascha Silva Sandy, Gilda Porta and 5 more

Abstract readMulticenter Study
PubMed Full text at PMC Publisher
In one paragraph

Article in Journal of pediatric gastroenterology and nutrition, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

15 authors.

Leticia Drumond AlbertoHospital das Clínicas da Universidade Federal de Minas Gerais, Belo Horizonte, Brazil.ORCID https://orcid.org/0000-0001-6383-7690
Eleonora Druve Tavares FagundesHospital das Clínicas da Universidade Federal de Minas Gerais, Belo Horizonte, Brazil.
Adriana Teixeira RodriguesHospital das Clínicas da Universidade Federal de Minas Gerais, Belo Horizonte, Brazil.
Thaís Costa Nascentes QueirozHospital das Clínicas da Universidade Federal de Minas Gerais, Belo Horizonte, Brazil.
Gustavo Valverde de CastroMedical School of Universidade Federal de Minas Gerais, Belo Horizonte, Brazil.
Carlos Oscar KielingHospital de Clínicas de Porto Alegre, Porto Alegre, Brazil.
Sandra Maria Gonçalves VieiraHospital de Clínicas de Porto Alegre, Porto Alegre, Brazil.
Natália Lamounier Dos Martires GuerraHospital das Clínicas da Universidade de São Paulo, São Paulo, Brazil.
Natascha Silva SandyHospital das Clínicas da Universidade de São Paulo, São Paulo, Brazil.
Gilda PortaHospital Infantil Menino Jesus, São Paulo, Brazil.
Irene Kazue MiuraHospital Infantil Menino Jesus, São Paulo, Brazil.
Maria Ângela Bellomo BrandãoHospital das Clínicas da Universidade Estadual de Campinas, Campinas, Brazil.
Gabriel HesselHospital das Clínicas da Universidade Estadual de Campinas, Campinas, Brazil.
Adriana Maria Alves de TommasoHospital das Clínicas da Universidade Estadual de Campinas, Campinas, Brazil.
Alexandre Rodrigues FerreiraHospital das Clínicas da Universidade Federal de Minas Gerais, Belo Horizonte, Brazil.

Funding

None
6 · The paper itself

Abstract

objectivesTo describe the clinical and laboratory characteristics and outcomes of pediatric hepatopulmonary syndrome (HPS) secondary to portal hypertension (PH) in Brazil.

methodsFifty-four pediatric patients diagnosed with PH and HPS according to the European Respiratory Society criteria were included in this multicenter retrospective study. Clinical and laboratory data at the time of diagnosing the underlying disease, 12 months before diagnosing HPS, at the time of diagnosing HPS, and at the time of the last consultation were collected from the medical records.

resultsPH was cirrhotic in 87% of patients. Biliary atresia was the predominant etiology (35.2%). The median age at the time of diagnosis was 7.8 years (interquartile range [IQR]: 4.7-10.8). Partial arterial oxygen pressure (PaO

conclusionsHPS remains asymptomatic during initial stages. SpO

Indexed as

Hepatopulmonary SyndromeHypertension, PortalAdolescentBiliary AtresiaBrazilChildChild, PreschoolFemaleHemoglobinsHumansLiver CirrhosisLiver TransplantationMaleRetrospective StudiesSurvival RateHemoglobinshypoxemialiver cirrhosisliver transplantation

Identifiers

PMID41347271
PMCPMC12864179

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.