ReviewFrontiers in oral health2025
Oral health-related quality of life in head and neck cancer: a systematic review.
Review in Frontiers in oral health, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
3 citing papers in PubMed.
- Extracellular Vesicles in Head and Neck Cancer-A Systematic Review.Journal of extracellular biology · 2026Review
- Dose-Dependence Relationship Between Radiotherapy and Oral Mucositis in Patients With Head and Neck Cancer: A Retrospective Study.International journal of dentistry · 2026Article
- Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
6 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Objectives: Head and Neck Cancer (HNC) is a devastating disease with significant mortality and morbidity. Patients suffer from compromised quality of life, due to the impact of the disease and its treatment on oral health and related functions. The aim of this systematic review was to identify the effects of HNC on oral health related quality of life (OHQoL). Methods: The protocol followed PRISMA-2020 guidelines. Literature search was conducted in electronic databases (PSYC-INFO, EMBASE, OVID-MEDLINE, SCOPUS, and WEB OF SCIENCE) at three time points, yielding 1198 records. Abstracts and full-texts were screened, and 101 eligible articles were identified. The risk of bias assessment was conducted using Joanna Briggs Institute critical appraisal tools. Narrative data synthesis was conducted under broad themes that influenced OHQoL; patient factors, diagnosis and treatment, and post treatment. Results: Studies were published between 2001 and 2024, a growing interest in OHQoL research was noted over time. 70.3% of the studies used oral health impact profile (OHIP-14) for OHQoL assessment. Among patient factors, low socioeconomic status, being without a partner and underweight were associated with worse scores. OHQoL varied with anatomical location of HNC, treatment modalities and their side effects such as mucositis and xerostomia. Prosthetic rehabilitation positively influenced OHQoL post-treatment. Conclusions: OHQoL assessment is critical in HNC patients from diagnosis, during treatment and beyond. It is influenced by factors related to sociodemographic, diagnosis, treatment, reconstruction and rehabilitation. The findings of this study can inform and guide clinicians to update supportive care and existing management of HNC and OPMD patients.
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