Evidence map›Paper›PMID 41347225›Full record

ArticleFrontiers in oral health2025

The first 1,000 days of life and early childhood caries: closing the global data gap.

Moréniké Oluwátóyìn Foláyan, Balgis Gaffar, Carlos Alberto Feldens, Robert J Schroth, Francisco Ramos-Gomez, Jorma I Virtanen, Hyewon Lee, Abiola Adeniyi, Maha El Tantawi

Abstract read
In one paragraph

Article in Frontiers in oral health, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Review
  2. Article
  3. Article
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Moréniké Oluwátóyìn FoláyanEarly Childhood Caries Advocacy Group, University of Manitoba, Winnipeg, MB, Canada.
Balgis GaffarEarly Childhood Caries Advocacy Group, University of Manitoba, Winnipeg, MB, Canada.
Carlos Alberto FeldensEarly Childhood Caries Advocacy Group, University of Manitoba, Winnipeg, MB, Canada.
Robert J SchrothEarly Childhood Caries Advocacy Group, University of Manitoba, Winnipeg, MB, Canada.
Francisco Ramos-GomezEarly Childhood Caries Advocacy Group, University of Manitoba, Winnipeg, MB, Canada.
Jorma I VirtanenEarly Childhood Caries Advocacy Group, University of Manitoba, Winnipeg, MB, Canada.
Hyewon LeeSchool of Dentistry, Dental Research Institute, Seoul National University, Seoul, Republic of Korea.
Abiola AdeniyiSchool of Public and Global Affairs, Fairleigh Dickinson University, Vancouver, BC, Canada.
Maha El TantawiEarly Childhood Caries Advocacy Group, University of Manitoba, Winnipeg, MB, Canada.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The first 1,000 days of life represent a critical window for preventing Early Childhood Caries (ECC). However, a significant global data gap obscures the true scale of ECC within this critical period. This review aims to systematically examine the global availability of ECC data for children under 36 months, discuss age-specific prevalence trends, and synthesize evidence to highlight the implications of missing data. A comprehensive analysis of a global dataset reporting ECC prevalence across 193 United Nations member states (2007-2017) was conducted. Analysis of the data was organized by the World Health Organization Region. The analysis revealed a profound data gap: 73.6% of countries had no data for children under 36 months, and only 19.7% had current data. Where data existed, rates approach or exceed 50% in some countries (e.g., Egypt: 69.6%, Mongolia: 47.5%), indicating that ECC is often well-established in the first 1,000 days of life. Significant regional disparities were identified, with the highest burden in the European Region, the Eastern Mediterranean Region, and the Western Pacific Region. Even within regions, there are extreme disparities in prevalence between countries (e.g., Kuwait at 3.0% vs. Egypt at 69.6% in the Middle East; Finland at 0.3% vs. Kazakhstan at 45.0% in Europe). The scarcity of data and high prevalence rates highlight a public oral health problem in infancy. Closing this global data gap is an essential first step to mobilize resources and implement targeted, effective prevention strategies where we can have the greatest impact.

Indexed as

early childhood cariesglobal healthhealth inequitieshealth policymaternal and child healthpregnancy

Identifiers

PMID41347225
PMCPMC12672514

What OpenQuestion holds

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LicenceCC BY
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.