Evidence map›Paper›PMID 41347128›Full record

SynthesisFrontiers in endocrinology2025

Charting the growth of idiopathic short stature research: a 32-year bibliometric study of global advances.

Zhao Wang, Zhendong Gao, Yongdie Huang, Zhen Li, Fei Luo, Tao Li, Yu Zhang, Lili Lin, Shouchuan Wang, Jin Ye

Abstract readSystematic Review
In one paragraph

Synthesis in Frontiers in endocrinology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Zhao Wang *Department of Pediatrics, Affiliated Hospital of Nanjing University of Chinese Medicine, Nanjing, China.
Zhendong Gao *Department of Thoracic Surgery and State Key Laboratory of Genetics and Development of Complex Phenotypes, Fudan University Shanghai Cancer Center, Shanghai, China.
Yongdie Huang *Department of Pediatrics, Affiliated Hospital of Nanjing University of Chinese Medicine, Nanjing, China.
Zhen LiJinan Shizhong District Ganshiqiao Sub-district Office Jingqi Road Community Health Service Station, Jinan, China.
Fei LuoDepartment of Pediatrics, Affiliated Hospital of Nanjing University of Chinese Medicine, Nanjing, China.
Tao LiDepartment of Pediatrics, Affiliated Hospital of Nanjing University of Chinese Medicine, Nanjing, China.
Yu ZhangJiangyin Affiliated Hospital of Nanjing University of Traditional Chinese Medicine, Jiangyin, China.
Lili LinDepartment of Pediatrics, Affiliated Hospital of Nanjing University of Chinese Medicine, Nanjing, China.
Shouchuan WangDepartment of Pediatrics, Affiliated Hospital of Nanjing University of Chinese Medicine, Nanjing, China.
Jin YeDepartment of Pediatrics, Affiliated Hospital of Nanjing University of Chinese Medicine, Nanjing, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Introduction: Idiopathic short stature (ISS) is a common paediatric endocrinological disorder defined by a height > two standard deviations (SDs) below the mean for age, sex, and ethnicity without an identifiable cause. This condition accounts for 60-80% of short stature cases in children and presents with complex and heterogeneous aetiology. ISS-related research has expanded rapidly over the past three decades; however, a comprehensive bibliometric analysis outlining its developmental trajectory and identifying emerging research priorities remains unavailable. Therefore, using network visualisation tools, we mapped 32 years of research to identify key trends, influential contributors, relevant journals, and emerging directions in ISS. Methods: Publications related to ISS in children, published between January 1993 and December 2024, were retrieved from the Web of Science Core Collection. Bibliometric and visual analyses were conducted using CiteSpace 6.1.R6, VOSviewer 1.6.20 and R package Bibliometrix. The analysis examined multiple dimensions, including annual publication trends, country and institutional contributions, collaboration networks, influential authors and journals, keyword evolution, and co-cited references to map the global ISS research landscape. We retrieved clinical trials published between 1993 and 2024 from the PubMed database to analyze the clinical progress in this field. Results: A total of 1, 567 articles were included in the analysis. The volume of publications in the ISS field has steadily increased over time. The United States of America contributed the most publications. Leiden University in the Netherlands produced the highest number of institutional publications. Wit authored the greatest number of publications, whereas Ranke had the highest number of citations. Discussion: This study systematically mapped the developmental trajectory and thematic evolution of ISS research over the past three decades using a comprehensive bibliometric analysis. The findings identified key contributors and research hotspots, providing valuable insights and reference points to guide future investigations.

Indexed as

BibliometricsBiomedical ResearchBody HeightDwarfismGrowth DisordersChildHumansbibliometric analysisendocrinologygrowth hormoneidiopathic short statureprecision medicine

Identifiers

PMID41347128
PMCPMC12672232

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.