Evidence map›Paper›PMID 41347015›Full record

ArticleClinical case reports2025

Brown Tumors Mimicking Skeletal Metastases: A Diagnostic Pitfall in Primary Hyperparathyroidism.

Uzma Akbar, Osama Ahmad, Fatima Sajjad, Khawar Saeed, Umer Dawar, Muhammad Salman Shah, Abdullah Afridi, Kamil Ahmad Kamil

Abstract read
In one paragraph

Article in Clinical case reports, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Uzma AkbarKhyber Teaching Hospital Peshawar Pakistan.
Osama AhmadKhyber Medical College Peshawar Pakistan.
Fatima SajjadKhyber Medical College Peshawar Pakistan.ORCID https://orcid.org/0009-0009-8861-0367
Khawar SaeedKhyber Teaching Hospital Peshawar Pakistan.
Umer DawarKhyber Teaching Hospital Peshawar Pakistan.
Muhammad Salman ShahKhyber Teaching Hospital Peshawar Pakistan.
Abdullah AfridiKhyber Medical College Peshawar Pakistan.
Kamil Ahmad KamilInternal Medicine Department Mirwais Regional Hospital Kandahar Afghanistan.ORCID https://orcid.org/0009-0000-8208-0689

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Brown tumors are rare but important manifestations of primary hyperparathyroidism (PHPT). These benign, fibrotic, and erosive bony lesions result from localized rapid osteoclastic activity driven by excessive parathyroid hormone levels. Although brown tumors are considered one of the most pathognomonic signs of PHPT, they are infrequently encountered in clinical practice. They closely mimic malignant osteolytic processes, posing a diagnostic challenge, especially in cases of undiagnosed hyperparathyroidism. Radiographic findings often resemble those of metastatic bone disease or primary bone malignancies.

Indexed as

brown tumorscase reportosteolytic lesionsprimary hyperparathyroidism

Identifiers

PMID41347015
PMCPMC12672390

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.