SynthesisFrontiers in medicine2025
Efficacy of exercise-based prehabilitation for patients undergoing elective spinal surgery: a systematic review and meta-analysis.
Synthesis in Frontiers in medicine, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
1 citing paper in PubMed.
- Depressive symptoms score and risk of incident spinal pain in middle-aged and elderly populations: a prospective cohort study based on china health and retirement longitudinal study data.European journal of physical and rehabilitation medicine · 2026Article
Corrections and comments
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Authors and funding
4 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Background: The study aimed to investigate the efficacy of exercise-based prehabilitation for preoperative and postoperative outcomes in patients undergoing elective spinal surgery. Methods: A total of five databases were searched from their inception to March 2025 with no date restrictions. Standardized mean differences (SMDs) and mean differences (MDs) with 95% confidence intervals (CIs) were pooled using random effects models. The certainty of the evidence was assessed using the Grading of Recommendations, Assessment, Development, and Evaluation (GRADE) approach. Results: In total, six studies with 365 participants were included in this study. Preoperative (after prehabilitation): Exercise-based prehabilitation produced modest improvements compared to controls for back pain (SMD -0.32, 95% CI -0.54 to -0.11; Conclusion: Exercise-based prehabilitation provides consistent small-to-moderate standardized benefits for most preoperative outcomes and shows a favorable signal for early postoperative back pain in adults undergoing elective spinal surgery. However, evidence for sustained intermediate- and long-term postoperative improvements is not established with current data. Systematic Review Registration: CRD420251120535, https://www.crd.york.ac.uk/PROSPERO/view/CRD420251120535.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.