Evidence map›Paper›PMID 41346925›Full record

ArticlePlastic and reconstructive surgery. Global open2025

Neurotized Dual-pedicle Deep Inferior Epigastric Perforator Flap With Vascularized Lymph Node Transfer for Unilateral Breast Reconstruction.

Janak A Parikh, Yousef Tanas, Joao Bombardelli, Suat Morkuzu, Aldona J Spiegel

Abstract read
In one paragraph

Article in Plastic and reconstructive surgery. Global open, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Janak A ParikhFrom the Institute for Reconstructive Surgery, Houston Methodist Hospital, Weill Cornell Medical College, Houston, TX.
Yousef TanasFrom the Institute for Reconstructive Surgery, Houston Methodist Hospital, Weill Cornell Medical College, Houston, TX.
Joao BombardelliFrom the Institute for Reconstructive Surgery, Houston Methodist Hospital, Weill Cornell Medical College, Houston, TX.
Suat MorkuzuFrom the Institute for Reconstructive Surgery, Houston Methodist Hospital, Weill Cornell Medical College, Houston, TX.
Aldona J SpiegelFrom the Institute for Reconstructive Surgery, Houston Methodist Hospital, Weill Cornell Medical College, Houston, TX.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: We describe clinical outcomes of combining a dual-pedicle deep inferior epigastric perforator (DIEP) flap, direct neurotization, and vascularized lymph node transfer (VLNT) for unilateral reconstruction in patients with breast cancer-related lymphedema or high risk of lymphedema. Methods: A retrospective review identified consecutive patients who underwent the composite procedure by a single surgeon from February 2018 to February 2020. Lymphedema status and breast sensation were evaluated clinically at routine follow-up (median, 11.5 mo [range, 9.9-24.5 mo]). Results: Five women (mean age 49 y, mean body mass index 23 kg/m²) underwent neurotized dual-pedicle DIEP with VLNT, 1 immediate and 4 delayed reconstructions. Mean operative time was 488 minutes (median, 480 min [range, 390-555 min]). Length of stay averaged 3.5 days (range, 3-4 d). No total or partial flap loss, donor-site hernia, seroma, hematoma, wound dehiscence, or 30-day reoperations occurred. Four patients experienced complete clinical resolution of upper extremity lymphedema; the remaining patient improved from stage II to stage I disease and continues compression therapy. All patients reported protective sensation in the reconstructed breast by 6 months. Secondary symmetry refinements included fat grafting (4 patients; mean 66 mL) and 1 implant augmentation. No donor-site lower extremity lymphedema was observed. Conclusions: Combining a dual-pedicle DIEP flap, flap neurotization, and VLNT is technically feasible and, in this pilot series, achieved reliable breast reconstruction while simultaneously addressing lymphedema and sensory restoration without added morbidity.

Identifiers

PMID41346925
PMCPMC12674155

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.