ArticleCureus2025
Methamphetamine Overdose and Hyperthermia in a 41-Year-Old Man Found Unresponsive.
Article in Cureus, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Authors and funding
7 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
This case examines the death of a 41-year-old man due to acute methamphetamine toxicity and severe hyperthermia. The patient was found unresponsive with a pulse and spontaneous respirations along a beach in Southeast Texas. Local weather at noon in late August was reported as 92°F (33.3°C) with 60% humidity. On arrival at the emergency department, he was unresponsive with agonal respirations and no palpable pulse. His core body temperature was 108.6°F (42.6°C) measured rectally, one of the highest temperatures recorded in a patient with a methamphetamine overdose who had a pulse and was breathing. Despite aggressive resuscitation and active cooling for 30 minutes, he was pronounced dead with a final temperature of 104.3°F (40.2°C). Postmortem toxicology from femoral blood revealed a methamphetamine concentration of 680 ng/mL and an amphetamine concentration of 55 ng/mL. This case provides an opportunity to discuss the multiple mechanisms through which stimulants contribute to hyperthermia as well as potential treatment strategies.
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