Evidence map›Paper›PMID 41346727›Full record

ArticleSAGE open medicine2025

Traumatic brain injury outcomes and mortality predictors in Eastern India: An observational study.

Harendra Kumar, Anil Kumar, Rachith Sridhar, Abdul Hakeem, Deepak Kumar, Abdul Vakil Khan, Anurag Kumar, Majid Anwer, Rekha Kumari, Sanjay Kumar

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Article in SAGE open medicine, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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0citing papers in PubMed
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1 · What the graph read from it

What it found

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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

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Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

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5 · Who and what money

Authors and funding

10 authors.

Harendra KumarDepartment of Trauma Surgery and Critical Care, All India Institute of Medical Sciences, Patna, Bihar, India.ORCID https://orcid.org/0009-0000-6646-1449
Anil KumarDepartment of Trauma Surgery and Critical Care, All India Institute of Medical Sciences, Patna, Bihar, India.ORCID https://orcid.org/0000-0002-8271-5784
Rachith SridharDepartment of Trauma Surgery and Critical Care, All India Institute of Medical Sciences, Patna, Bihar, India.ORCID https://orcid.org/0000-0002-4493-8514
Abdul HakeemDepartment of Trauma Surgery and Critical Care, All India Institute of Medical Sciences, Patna, Bihar, India.ORCID https://orcid.org/0000-0002-2128-1732
Deepak KumarDepartment of Trauma Surgery and Critical Care, All India Institute of Medical Sciences, Patna, Bihar, India.ORCID https://orcid.org/0009-0003-9733-0101
Abdul Vakil KhanDepartment of Trauma Surgery and Critical Care, All India Institute of Medical Sciences, Patna, Bihar, India.
Anurag KumarDepartment of Trauma Surgery and Critical Care, All India Institute of Medical Sciences, Patna, Bihar, India.ORCID https://orcid.org/0000-0002-5849-3958
Majid AnwerDepartment of Trauma Surgery and Critical Care, All India Institute of Medical Sciences, Patna, Bihar, India.ORCID https://orcid.org/0000-0003-4193-0805
Rekha KumariDepartment of Trauma Surgery and Critical Care, All India Institute of Medical Sciences, Patna, Bihar, India.ORCID https://orcid.org/0009-0007-7003-6251
Sanjay KumarDepartment of Trauma Surgery and Critical Care, All India Institute of Medical Sciences, Patna, Bihar, India.ORCID https://orcid.org/0000-0001-6204-3119

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Title: Traumatic brain injury outcomes and mortality predictors in Eastern India: A prospective observational cohort study. Objective: To evaluate clinical outcomes and identify predictors of mortality in patients with traumatic brain injury treated at a tertiary trauma centre in Eastern India. Methods: This was a single-centre prospective observational cohort study conducted at AIIMS, Patna, Bihar, Eastern India, over 18 months (July 2023-January 2025). A total of 383 consecutive patients with traumatic brain injury were enrolled based on predefined inclusion and exclusion criteria. Demographic, clinical, radiological, and management variables were recorded. Functional outcomes were assessed at discharge, 3 months, 6 months months using the Glasgow Outcome Scale-Extended. Logistic regression was used to identify independent predictors of mortality and poor functional outcome. Results: The mean age was 34.4 ± 15.2 years, and most patients were male (68.9%). Road traffic accidents were the leading cause of injury (68.9%). Based on admission Glasgow Coma Scale, 53.3% had mild, 20.1% moderate, and 26.6% severe traumatic brain injury. Mortality was 23.5% at discharge and 24.5% at 6 months, with 95.7% of deaths occurring within the first month. Favourable outcomes (Glasgow Outcome Scale-Extended 6-8) were observed in 66.1% at 3 months and 70.8% at 6 months. Severe traumatic brain injury was significantly associated with 6-month mortality ( Conclusions: Traumatic brain injury in Eastern India predominantly affects young males in road traffic accidents. While functional recovery appeared to improve between discharge and 6 months, severe injuries and specific radiological features may be associated with increased mortality. Burr-hole surgery and craniotomy may be linked to more favourable outcomes compared with craniectomy. Strengthening trauma systems and timely surgical interventions may help improve outcomes in resource-limited settings.

Indexed as

developing countriesGOSE outcomesmortalitytomographytraumatic brain injurytreatment outcomeX-ray computed

Identifiers

PMID41346727
PMCPMC12673051

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.