Evidence map›Paper›PMID 41346581›Full record

ArticleFrontiers in immunology2025

A novel

Feng Chen, Siyu Lei, Caihui Yuan, Zhongjin Xu, Qian Wan, Chongjun Wu, Ting Xiong

Abstract readCase Reports
In one paragraph

Article in Frontiers in immunology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Feng ChenDepartment of Hematology, Jiangxi Provincial Children's Hospital, Nanchang, China.
Siyu LeiDepartment of Hematology, Jiangxi Provincial Children's Hospital, Nanchang, China.
Caihui YuanDepartment of Radiology, Jiangxi Provincial Children's Hospital, Nanchang, China.
Zhongjin XuDepartment of Hematology, Jiangxi Provincial Children's Hospital, Nanchang, China.
Qian WanDepartment of Hematology, Jiangxi Provincial Children's Hospital, Nanchang, China.
Chongjun WuDepartment of Hematology, Jiangxi Provincial Children's Hospital, Nanchang, China.
Ting XiongDepartment of Endocrine Genetics and Metabolism, Jiangxi Provincial Children's Hospital, Nanchang, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Objective: As a critical immune checkpoint, cytotoxic T-lymphocyte-associated protein 4( Methods: Trio-based whole-exome sequencing (WES) was performed on peripheral blood samples from a 6-year-old female with refractory AIHA and her parents. Candidate variants were validated by Sanger sequencing. Structural modeling of mutant Results: A Conclusion: The

Indexed as

Anemia, Hemolytic, AutoimmuneCTLA-4 AntigenSequence DeletionChildExome SequencingFemaleHEK293 CellsHumansCTLA-4 AntigenCTLA4 protein, humanautoimmune hemolytic anemiachildrenCTLA-4refractory AIHAvariant

Identifiers

PMID41346581
PMCPMC12672875

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.