Evidence map›Paper›PMID 41346414›Full record

ReviewBiomaterials research2025

Astaxanthin-Based Biomaterials for Tissue Repair and Drug Delivery Systems.

Yibing Wang, Huaqian Xue, Chuchu Sun, Qiancheng Gu, Liang Chen, Zhengqiu Lin, Liyuan Xu, Lanjie Lei, Qiujie Li, Zhangwei Zhao

Abstract readReview
PubMed Full text at PMC Publisher
In one paragraph

Review in Biomaterials research, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Yibing WangKey Laboratory of Artificial Organs and Computational Medicine of Zhejiang Province, Shulan International Medical College, Institute of Translational Medicine, Zhejiang Shuren University, Hangzhou, Zhejiang 310015, China.
Huaqian XueKey Laboratory of Artificial Organs and Computational Medicine of Zhejiang Province, Shulan International Medical College, Institute of Translational Medicine, Zhejiang Shuren University, Hangzhou, Zhejiang 310015, China.
Chuchu SunThe Third Affiliated Hospital of Wenzhou Medical University, Wenzhou 325200, China.
Qiancheng GuKey Laboratory of Artificial Organs and Computational Medicine of Zhejiang Province, Shulan International Medical College, Institute of Translational Medicine, Zhejiang Shuren University, Hangzhou, Zhejiang 310015, China.
Liang ChenKey Laboratory of Artificial Organs and Computational Medicine of Zhejiang Province, Shulan International Medical College, Institute of Translational Medicine, Zhejiang Shuren University, Hangzhou, Zhejiang 310015, China.
Zhengqiu LinThe Third Affiliated Hospital of Wenzhou Medical University, Wenzhou 325200, China.
Liyuan XuKey Laboratory of Artificial Organs and Computational Medicine of Zhejiang Province, Shulan International Medical College, Institute of Translational Medicine, Zhejiang Shuren University, Hangzhou, Zhejiang 310015, China.
Lanjie LeiKey Laboratory of Artificial Organs and Computational Medicine of Zhejiang Province, Shulan International Medical College, Institute of Translational Medicine, Zhejiang Shuren University, Hangzhou, Zhejiang 310015, China.ORCID https://orcid.org/0000-0003-1773-1646
Qiujie LiKey Laboratory of Artificial Organs and Computational Medicine of Zhejiang Province, Shulan International Medical College, Institute of Translational Medicine, Zhejiang Shuren University, Hangzhou, Zhejiang 310015, China.
Zhangwei ZhaoThe Third Affiliated Hospital of Wenzhou Medical University, Wenzhou 325200, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Astaxanthin (AST), a potent bioactive compound known for its exceptional antioxidant, anti-inflammatory, and anti-apoptotic capacities, has been widely applied in advanced biomedical domains, including regenerative tissue engineering and targeted drug delivery systems. However, its chemical instability limits broader applications. To address this issue, various multifunctional biomaterials, such as nanoliposomes, nanoparticles, glass microspheres, and algal calcium beads, have been employed to stabilize AST and enhance its therapeutic efficacy. This review provides a comprehensive overview of AST, examines its mechanisms of action, and discusses the development and biomedical applications of AST-based biomaterials. We demonstrate the excellent properties and potential applications of these biomaterials in various biomedical contexts, outline existing challenges, and propose future directions to optimize their design and advance their clinical translation.

Identifiers

PMID41346414
PMCPMC12673025

What OpenQuestion holds

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LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.