Evidence map›Paper›PMID 41346382›Full record

ArticleFrontiers in neurology2025

Cathodal tDCS and robotic therapy for upper limb rehabilitation in chronic stroke: a randomized controlled trial.

Jin Chen, Jingang Du, Chunfang Wang, Hongli Yu

Abstract read
In one paragraph

Article in Frontiers in neurology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Jin ChenDepartment of Rehabilitation Medical, The Third Central Hospital of Tianjin, Tianjin, China.
Jingang DuTianjin Union Medical Centre, Tianjin Rehabilitation Institute, Tianjin, China.
Chunfang WangTianjin Union Medical Centre, Tianjin Rehabilitation Institute, Tianjin, China.
Hongli YuTianjin Key Laboratory of Bioelectromagnetic Technology and Intelligent Health, Hebei University of Technology, Tianjin, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Introduction: This randomized controlled trial evaluated the effect of contralesional cathodal transcranial direct current stimulation (ctDCS) combined with robotic therapy (RT) on upper limb recovery in patients with chronic subcortical ischemic stroke. Methods: Thirty-one participants were randomized to receive either active ctDCS or sham stimulation during RT, administered five times per week for four weeks. Outcomes were assessed using clinical rehabilitation scales and robotic evaluation of movement parameters at baseline, immediately post-intervention, and at two-week follow-up. Results: The active group demonstrated significantly greater improvement in Upper Extremity Fugl-Meyer Assessment, with a between-group difference of 4.61 (95% CI: 51.36 to 55.46, p = 0.023) post-intervention. Functional efficiency (mean difference: 1.82, 95% CI: 9.13 to 12.00) and movement speed (mean difference: 3.46, 95% CI: 51.60 to 56.74) also favored the active group. Conclusion: These findings suggest that combining ctDCS with RT may enhance the efficiency of specific upper limb motor tasks in patients with chronic subcortical ischemic stroke, compared to RT alone.

Indexed as

cathodal transcranial direct current stimulationprimary motor cortexrobotic therapystrokeupper limb rehabilitation

Identifiers

PMID41346382
PMCPMC12672312

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.