Evidence map›Paper›PMID 41346350›Full record

ArticleGlobal cardiology science & practice2025

Recurrent, isolated left main coronary artery stenosis in a young female.

Brianna Skaff, Jeff Spindel, Melissa Miller, Maya Ignaszewski

Abstract readCase Reports
In one paragraph

Article in Global cardiology science & practice, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Brianna SkaffDivision of Internal Medicine, University of Kentucky, 800 Rose St, Lexington, KY 40536.
Jeff SpindelDivision of Cardiology, Gill Heart and Vascular Institute, University of Kentucky.
Melissa MillerDivision of Cardiology, Gill Heart and Vascular Institute, University of Kentucky.
Maya IgnaszewskiDivision of Cardiology, Gill Heart and Vascular Institute, University of Kentucky.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

A 21-year-old female with no prior cardiac history presented multiple times with chest pain and elevated cardiac biomarkers. Single-photon emission computed tomography revealed a reversible perfusion defect, and coronary angiography was attempted, but was aborted. After multiple similar presentations without angiography, the patient suffered ST-elevation myocardial infarction. Coronary angiography revealed 99% subtotal occlusion of the left main coronary artery and a reduced ejection fraction of 20% complicated by cardiac arrest and cardiogenic shock requiring mechanical circulatory support-assisted percutaneous coronary intervention and veno-arterial extracorporeal membrane oxygenation as a bridge to recovery. An extensive workup did not reveal any secondary causes. Despite frequent follow-up and strict adherence to dual antiplatelet therapy, she developed recurrent angina and was found to have severe in-stent restenosis of the left main coronary artery, requiring two-vessel coronary artery bypass grafting. Despite normal blood counts prior to surgery, post-surgical labs revealed blast-phase acute myeloid leukemia, prompting the initiation of chemotherapy.

Identifiers

PMID41346350
PMCPMC12673872

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.