ArticleBioconjugate chemistry2025
Effects of N
Bhoomika Pandit, Emmett Hanson, Hilal Dagci, Qingying Yang, Mehmet V Yigit, Maksim Royzen
Abstract read
In one paragraphArticle in Bioconjugate chemistry, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
2 · The registryThe trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
3 · Its place in the literatureWho cites it
0 citing papers in PubMed.
No citing paper in PubMed yet.
4 · The recordCorrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
5 · Who and what moneyAuthors and funding
6 authors.
Bhoomika PanditDepartment of Chemistry, University at Albany, State University of New York, 1400 Washington Avenue, Albany, New York 12222, United States.
Emmett HansonDepartment of Chemistry, University at Albany, State University of New York, 1400 Washington Avenue, Albany, New York 12222, United States.
Hilal DagciDepartment of Chemistry, University at Albany, State University of New York, 1400 Washington Avenue, Albany, New York 12222, United States.
Qingying YangDepartment of Chemistry, University at Albany, State University of New York, 1400 Washington Avenue, Albany, New York 12222, United States.
Mehmet V YigitDepartment of Chemistry, University at Albany, State University of New York, 1400 Washington Avenue, Albany, New York 12222, United States.ORCID 0000-0002-4349-3701 Maksim RoyzenDepartment of Chemistry, University at Albany, State University of New York, 1400 Washington Avenue, Albany, New York 12222, United States.ORCID 0000-0002-2930-2171 Funding
DNA nanotechnology and synthetic biology for AI-supported detection and precision therapeuticsR35GM156250 · NIGMS · STATE UNIVERSITY OF NEW YORK AT ALBANY · PI Mehmet Veysel Yigit · 2025 to 2026
$779kSynthesis and non-chromatographic purification of long RNA oligonucleotides containing naturally occurring modificationR21HG012257 · NHGRI · STATE UNIVERSITY OF NEW YORK AT ALBANY · PI ROYZEN, MAKSIM · 2022 to 2024
$620kNHGRI NIH HHS R21 HG012257NIGMS NIH HHS R35 GM156250
6 · The paper itselfAbstract
CRISPR-Cas12a is a versatile biosensing platform that detects sequence-specific DNA or RNA targets via a CRISPR RNA (crRNA) guide. While Cas12a's specificity is dictated by its crRNA, chemical modifications within the crRNA can influence nuclease performance. Here, we examined the effects of two well-known RNA modifications, N
Indexed as
5-MethylcytosineAdenosineBacterial ProteinsCRISPR-Associated ProteinsCRISPR-Cas SystemsEndodeoxyribonucleasesRNA, Guide, CRISPR-Cas Systems5-MethylcytosineAdenosineBacterial ProteinsCas12a proteinCRISPR-Associated ProteinsEndodeoxyribonucleasesN-methyladenosineRNA, Guide, CRISPR-Cas Systems
Identifiers
PMID41346237
PMCPMC12715751
What OpenQuestion holds
Textmetadata
LicenceCC BY
Read underepoch 390