ArticleJournal of cardiovascular electrophysiology2026
Assessing the Feasibility of Radiofrequency Wire-Based Transseptal Puncture in Fluoroscopy-Only Pulsed Field Ablation Workflows.
Article in Journal of cardiovascular electrophysiology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
4 citing papers in PubMed.
- TRUST-AF: comparison of conventional SL0 sheath exchange versus direct large-bore faradrive sheath access for fluoroscopy-guided transseptal puncture in pulsed field ablation.Journal of interventional cardiac electrophysiology : an international journal of arrhythmias and pacing · 2026Article
- Crossing the Septum: Step-by-Step Anatomy, Technique, and Enabling Technologies in Transseptal Puncture for Atrial Fibrillation and Electrophysiological Procedures.Biomedicines · 2026Review
- Evolution of Radiofrequency Transseptal Puncture Devices.Medical devices (Auckland, N.Z.) · 2026Review
- Assessing the Feasibility of Radiofrequency Wire-Based Transseptal Puncture in Fluoroscopy-Only Pulsed Field Ablation Workflows.Journal of cardiovascular electrophysiology · 2026Article
Corrections and comments
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Authors and funding
6 authors.
Funding
Abstract
introductionSafe and effective left atrial (LA) access is a critical step in catheter ablation procedures. While radiofrequency wire (RFW)-based transseptal puncture (TSP) offers advantages over mechanical needle (MN) techniques, adoption in Europe has been limited due to concerns about the need for costly adjunctive imaging. This study evaluated the feasibility of using RFW-based TSP within fluoroscopy-only pulsed field ablation (PFA) procedures.
methodsA retrospective, single-center chart review of consecutive PFA cases was conducted. TSP was performed using either an MN or RFW, with MN serving as a feasibility benchmark. All procedures used the pentaspline PFA system under standard-of-care protocols, with fluoroscopy as the primary imaging modality.
resultsA total of 617 PFA procedures were analyzed (435 RFW, 182 MN). Baseline characteristics were similar. LA access was successful in all RFW cases, with no significant difference in complication rates. Notably, no RFW cases required adjunctive echocardiography, compared to three in the MN group (0% vs. 1.6%, p < 0.01). Procedural times and fluoroscopy exposure were comparable. In patients with prior TSP, RFW enabled significantly faster and more consistent access than MN (8.1 ± 3.9 min vs. 11.1 ± 5.8 min, p < 0.01).
conclusionPurpose-built RFW systems demonstrated comparable safety and efficacy to MN-based devices in fluoroscopy-only PFA workflows, with added efficiency and predictability in complex anatomies. These findings suggest that the benefits of RFW can be realized without reliance on costly imaging modalities.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.