Evidence map›Paper›PMID 41346116›Full record

ArticlePlant communications2026

Engineering seed-specific gossypol-free cotton for human-safe consumption by harnessing the dominant-negative effect of the Gl

Xiangfei Cheng, Pengbao Wang, Xinchun Wang, Roshan Zameer, Lu Liu, Zhouqing Chen, Pengyu Wang, Jing Jiang, Chengde Yu, Baoliang Tian and 11 more

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Plant communications, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

21 authors.

Xiangfei ChengState Key Laboratory of Cotton Bio-breeding and Integrated Utilization, School of Life Sciences, Henan University, Kaifeng, Henan 475004, China; Center for Molecular Interactions and Translational Applications, School of Life Sciences, Henan University, Kaifeng, Henan 475004, China.
Pengbao WangState Key Laboratory of Cotton Bio-breeding and Integrated Utilization, School of Life Sciences, Henan University, Kaifeng, Henan 475004, China; Center for Molecular Interactions and Translational Applications, School of Life Sciences, Henan University, Kaifeng, Henan 475004, China.
Xinchun WangState Key Laboratory of Cotton Bio-breeding and Integrated Utilization, School of Life Sciences, Henan University, Kaifeng, Henan 475004, China; Center for Molecular Interactions and Translational Applications, School of Life Sciences, Henan University, Kaifeng, Henan 475004, China.
Roshan ZameerState Key Laboratory of Cotton Bio-breeding and Integrated Utilization, School of Life Sciences, Henan University, Kaifeng, Henan 475004, China.
Lu LiuState Key Laboratory of Cotton Bio-breeding and Integrated Utilization, School of Life Sciences, Henan University, Kaifeng, Henan 475004, China; Center for Molecular Interactions and Translational Applications, School of Life Sciences, Henan University, Kaifeng, Henan 475004, China.
Zhouqing ChenState Key Laboratory of Cotton Bio-breeding and Integrated Utilization, School of Life Sciences, Henan University, Kaifeng, Henan 475004, China.
Pengyu WangState Key Laboratory of Cotton Bio-breeding and Integrated Utilization, School of Life Sciences, Henan University, Kaifeng, Henan 475004, China.
Jing JiangState Key Laboratory of Cotton Bio-breeding and Integrated Utilization, School of Life Sciences, Henan University, Kaifeng, Henan 475004, China; Center for Molecular Interactions and Translational Applications, School of Life Sciences, Henan University, Kaifeng, Henan 475004, China.
Chengde YuState Key Laboratory of Cotton Bio-breeding and Integrated Utilization, School of Life Sciences, Henan University, Kaifeng, Henan 475004, China; Center for Molecular Interactions and Translational Applications, School of Life Sciences, Henan University, Kaifeng, Henan 475004, China.
Baoliang TianState Key Laboratory of Cotton Bio-breeding and Integrated Utilization, School of Life Sciences, Henan University, Kaifeng, Henan 475004, China.
Wei WangState Key Laboratory of Cotton Bio-breeding and Integrated Utilization, School of Life Sciences, Henan University, Kaifeng, Henan 475004, China.
Shunhe YuState Key Laboratory of Cotton Bio-breeding and Integrated Utilization, School of Life Sciences, Henan University, Kaifeng, Henan 475004, China.
Hui PanState Key Laboratory of Cotton Bio-breeding and Integrated Utilization, School of Life Sciences, Henan University, Kaifeng, Henan 475004, China; State Key Laboratory of Cotton Bio-breeding and Integrated Utilization, Institute of Cotton Research, Chinese Academy of Agricultural Sciences, Anyang, Henan 455000, China.
Huazhong ShiDepartment of Chemistry and Biochemistry, Texas Tech University, Lubbock, TX 79409, USA.
Cheng-Guo DuanKey Laboratory of Plant Design, National Key Laboratory of Plant Molecular Genetics, Shanghai Center for Plant Stress Biology, Center for Excellence in Molecular Plant Sciences, Chinese Academy of Sciences, Shanghai 200032, China.
Dongyun ZuoState Key Laboratory of Cotton Bio-breeding and Integrated Utilization, Institute of Cotton Research, Chinese Academy of Agricultural Sciences, Anyang, Henan 455000, China.
Lihong ZhaoState Key Laboratory of Cotton Bio-breeding and Integrated Utilization, Institute of Cotton Research, Chinese Academy of Agricultural Sciences, Anyang, Henan 455000, China.
Zhifang LiState Key Laboratory of Cotton Bio-breeding and Integrated Utilization, School of Life Sciences, Henan University, Kaifeng, Henan 475004, China; Center for Molecular Interactions and Translational Applications, School of Life Sciences, Henan University, Kaifeng, Henan 475004, China. Electronic address: 10140165@vip.henu.edu.cn.
Chun-Peng SongState Key Laboratory of Cotton Bio-breeding and Integrated Utilization, School of Life Sciences, Henan University, Kaifeng, Henan 475004, China. Electronic address: songcp@henu.edu.cn.
Guoli SongState Key Laboratory of Cotton Bio-breeding and Integrated Utilization, Institute of Cotton Research, Chinese Academy of Agricultural Sciences, Anyang, Henan 455000, China. Electronic address: sglzms@163.com.
Changsong ZouState Key Laboratory of Cotton Bio-breeding and Integrated Utilization, School of Life Sciences, Henan University, Kaifeng, Henan 475004, China; Center for Molecular Interactions and Translational Applications, School of Life Sciences, Henan University, Kaifeng, Henan 475004, China. Electronic address: zoucs@henu.edu.cn.

Funding

Non-US Government Research Support type
6 · The paper itself

Abstract

The global yield of cottonseed could meet the annual protein requirements of approximately half a billion people if gossypol were absent from the seeds. Here, we characterize the molecular mechanism by which the Gl

Indexed as

GossypiumGossypolPlant ProteinsSeedsGene Expression Regulation, PlantGenetic EngineeringHumansMutationPlants, Genetically ModifiedGossypolPlant Proteinsdominant-negative effectgenetically modified cropsgenetic regulatory networkGl(2)/Gl(3) tetramerhuman nutritionseed-specific gossypol-free cotton

Identifiers

PMID41346116
PMCPMC12903441

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.