ArticlePediatric allergy and immunology : official publication of the European Society of Pediatric Allergy and Immunology2025
Investigating the health economic burden of atopic disease in children from the EAT-On Study.
Article in Pediatric allergy and immunology : official publication of the European Society of Pediatric Allergy and Immunology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
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1 citing paper in PubMed.
- Investigating the health economic burden of atopic disease in children from the EAT-On Study.Pediatric allergy and immunology : official publication of the European Society of Pediatric Allergy and Immunology · 2025Article
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Authors and funding
7 authors.
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No grant is acknowledged in the PubMed record.
Abstract
backgroundThere is growing interest in the health economic burden of childhood diseases. This study aimed to compare healthcare costs between atopic and non-atopic children in a general UK population.
methodsParticipants were recruited from the EAT-On study which followed children originally seen from 3 months old and then 7-12 years. A health economics questionnaire (HEQ) collected data from 2018 to 2022 on the utilization of UK healthcare services and were valued using published unit costs for UK£2021. Mean (standard deviation) resource use and cost were estimated for atopic and non-atopic children, in addition to mean difference (95% confidence interval) between atopic and non-atopic children. Two-part logistic regression analyses were performed to examine the likelihood of a child incurring healthcare costs including variables associated with the level of cost incurred.
results625 children completed the HEQ; 33% reported zero healthcare costs over a 12-month period and 34.4% (215/625) had at least 1 atopic disease. Children with any atopic disease had higher total costs compared to those without atopic disease (mean difference £77 (95% CI -16.9, 170.6) per participant); if extrapolated to population level, this equated to £104.7 million more per year. Children with atopy were more likely to utilize hospital-based services compared to children without atopy (mean difference £104.3 (95% CI 36.2, 172.5) per participant). Being younger in the 7-12 y age bracket or coming from a lower income household (<£60,000/year) was associated with higher total healthcare costs.
conclusionChildren with atopy incur greater total healthcare costs compared to children without atopy.
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