Evidence map›Paper›PMID 41345971›Full record

ArticleThe Journal of physiology2026

Mechanism of CO

Raif Musa-Aziz, R Ryan Geyer, Seong-Ki Lee, Fraser J Moss, Walter F Boron

Abstract read
In one paragraph

Article in The Journal of physiology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. Role of channels in the ObioRxiv : the preprint server for biology · 2025
    Article
  5. Role of channels in thebioRxiv : the preprint server for biology · 2025
    Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

5 authors.

Raif Musa-AzizDepartment of Physiology and Biophysics, Institute of Biomedical Sciences, University of São Paulo, São Paulo, Brazil.ORCID 0000-0002-0386-4248
R Ryan GeyerDepartment of Physiology and Biophysics Case Western Reserve University School of Medicine, Cleveland, OH, USA.
Seong-Ki LeeDepartment of Physiology and Biophysics Case Western Reserve University School of Medicine, Cleveland, OH, USA.ORCID 0000-0003-1928-4392
Fraser J MossDepartment of Physiology and Biophysics Case Western Reserve University School of Medicine, Cleveland, OH, USA.ORCID 0000-0002-8519-6991
Walter F BoronDepartment of Physiology and Biophysics Case Western Reserve University School of Medicine, Cleveland, OH, USA.ORCID 0000-0003-4741-7287

Funding

Synthetic Antigen Binder CoreU54GM087519 · NIGMS · UNIVERSITY OF CHICAGO · PI JAVITCH, JONATHAN A · 2010 to 2017
$31.9M
PH REGULATION OF EXCITABLE INVERTEBRATE CELLSR01NS018400 · NINDS · YALE UNIVERSITY · PI BORON, WALTER F · 1985 to 2012
$5.1M
Mechanisms of oxygen off-loading from red blood cells in murine models of human diseaseR01HL160857 · NHLBI · CASE WESTERN RESERVE UNIVERSITY · PI BORON, WALTER F · 2022 to 2025
$2.6M
Fundação de Amparo à Pesquisa do Estado de São Paulo 13/11364-3Fundação de Amparo à Pesquisa do Estado de São Paulo 18/22855-1Fundação de Amparo à Pesquisa do Estado de São Paulo 2013/10780Multidisciplinary University Research Initiative N00014-16-1-2535NHLBI NIH HHS HL160857NHLBI NIH HHS R01 HL160857NIDDK NIH HHS DK8156NIGMS NIH HHS U54 GM087519NINDS NIH HHS NS18400NINDS NIH HHS R01 NS018400Office of Naval Research N00014-05-1-0345Office of Naval Research N00014-08-1-0532Office of Naval Research N00014-09-1-0246Office of Naval Research N00014-11-1-0889Office of Naval Research N00014-14-1-0716Office of Naval Research N00014-15-1-2060
6 · The paper itself

Abstract

The traditional view had been that dissolved gases cross membranes simply by dissolving in and diffusing through the membrane lipid. However, some membranes are impermeable to CO

Indexed as

AmmoniaAquaporin 1Carbon DioxideAnimalsBiological TransportHumansOocytesWaterXenopus laevisAmmoniaAQP1 protein, humanAquaporin 1Carbon DioxideWaterCO2 permeabilityosmotic water permeabilitySurface pHXenopus laevis oocytes

Identifiers

PMID41345971
PMCPMC12783978

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.