Evidence map›Paper›PMID 41345901›Full record

ArticleBMC plant biology2025

Screening and expression analysis of the NRAMP gene family in Kiwifruit under cadmium stress reveals the potential role of AcNRAMP7.

Xuechun Li, Hanbing Cai, Ping Tian, Ke Zhao, Jiaqiong Wan, Tuo Yin, Hanyao Zhang, Xiaozhen Liu

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in BMC plant biology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Xuechun LiYunnan Provincial Key Laboratory for Conservation and Utilization of In-forest Resource, Southwest Forestry University, Kunming, 650224, China.
Hanbing CaiKey Laboratory for Forest Resources Conservation and Utilization in the Southwest Mountains of China, Ministry of Education, Southwest Forestry University, Kunming, China.
Ping TianKey Laboratory of Biodiversity Conservation in Southwest China, National Forest and Grassland Administration, Southwest Forestry University, Kunming, Yunnan Province, 650224, China.
Ke ZhaoKey Laboratory for Forest Resources Conservation and Utilization in the Southwest Mountains of China, Ministry of Education, Southwest Forestry University, Kunming, China.
Jiaqiong WanKey Laboratory for Forest Resources Conservation and Utilization in the Southwest Mountains of China, Ministry of Education, Southwest Forestry University, Kunming, China.
Tuo YinYunnan Provincial Key Laboratory for Conservation and Utilization of In-forest Resource, Southwest Forestry University, Kunming, 650224, China.
Hanyao ZhangYunnan Provincial Key Laboratory for Conservation and Utilization of In-forest Resource, Southwest Forestry University, Kunming, 650224, China. zhanghanyao@swfu.edu.cn.
Xiaozhen LiuYunnan Provincial Key Laboratory for Conservation and Utilization of In-forest Resource, Southwest Forestry University, Kunming, 650224, China. 15198729095@swfu.edu.cn.

Funding

the Agricultural Joint Key Projects in Yunnan Province 202301BD070001-003the Rural Revitalization Science and Technology Project-Rural Revitalization Industry Key Technology Integration Demonstration Project 202304BP090005Yunnan Academician (Expert) Workstation Project 202305AF150020
6 · The paper itself

Abstract

The NRAMP gene family mediates the transport of divalent metal ions in plants and is critically involved in cadmium (Cd) accumulation and tolerance. In this study, 12 AcNRAMP genes were identified in the kiwifruit genome and phylogenetically classified into four distinct clades. Chromosomal localization analysis revealed that 11 AcNRAMP genes were unevenly distributed across seven chromosomes. Promoter cis-element analysis revealed that AcNRAMP genes contain motifs primarily associated with related to hormone responsiveness and environmental stress. Expression profiling demonstrated significant differential expression of three genes in the roots and two genes in the leaves. Based on RT-PCR analysis, we further propose a mechanistic model for AcNRAMP-mediated response to Cd stress: under high Cd conditions, transcript levels of AcNRAMP7 and AcNRAMP10 were downregulated in roots, whereas AcNRAMP6 was upregulated in leaves. This coordinated expression may limit Cd translocation into root tissues, mitigate cellular damage, and enhance plant tolerance, which was associated with reduced root growth. Our results provide valuable insights into the molecular mechanisms underlying Cd stress response in kiwifruit and establish a foundation for future functional studies on the AcNRAMP gene regulation.

Indexed as

ActinidiaCadmiumCation Transport ProteinsPlant ProteinsGene Expression ProfilingGene Expression Regulation, PlantMultigene FamilyPhylogenyPlant LeavesPlant RootsStress, PhysiologicalCadmiumCation Transport ProteinsPlant ProteinsCadmium stressExpression pattern analysisKiwifruitNRAMP

Identifiers

PMID41345901
PMCPMC12794262

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.