ArticleTropical medicine and health2025
Prevalence of schistosome infection among children under two years of age: a brief report from medium-to-high endemic regions of Schistosoma mansoni in Madagascar.
Article in Tropical medicine and health, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
1 citing paper in PubMed.
- Prevalence of multiple human intestinal parasites across diverse environments in Madagascar.PLoS neglected tropical diseases · 2026Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
24 authors.
Funding
Abstract
introductionSchistosome infections in early childhood can affect a child's growth and development, leading to lifelong consequences. Historically, monitoring and control of schistosomiasis have focused primarily on school-aged children leading to a knowledge gap on the magnitude of the prevalence of infections in younger age groups in many endemic countries. This study aimed to estimate the prevalence of schistosome infections among children under 2 years of age and describe its distribution in three regions of Madagascar endemic for Schistosoma mansoni, thereby informing public health strategies in the country.
methodsA cross-sectional study was conducted on a sample of 2018 children under 2 years of age recruited from 42 primary health care centres in the regions of Itasy, Bongolava and Amoron'i Mania, Madagascar, from March 2020 to June 2021. Urine samples were collected to perform an up-converting reporter particle lateral flow circulating anodic antigen assay (UCP-LF-CAA) for the detection of schistosome infections. To identify factors associated with the prevalence of schistosome infection, prevalence ratios with 95% CIs were estimated using mixed-effects Poisson regression.
resultsAmong 2018 sampled children with an average age of 9.6 months (SD = 1.2), the prevalence of schistosome infection was 6.2% [CI95%: 5.0, 7.8]. The prevalence estimates were similar across all population subgroups. We observed no statistically significant associations of schistosome infections in children with maternal age (p-value = 0.4110), education (p-value = 0.1281), occupation (p-value = 0.3333), child sex (p-value = 0.3692), urbanisation (p-value = 0.8272) or region of residence (p-value = 0.7425).
conclusionOur results show that the prevalence of schistosome infection in children under 2 years of age in Madagascar is significant. Given the high burden and long-term consequences of early schistosome infection, integrated and inclusive public health interventions that combine treatment, caregiver health education, with improvements in sanitation and access to clean water, are needed for children under 2 years of age in endemic settings.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.