ArticleBMC research notes2025
Improved genome assembly of Onygena corvina, a keratin-degrading fungus.
Article in BMC research notes, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
1 citing paper in PubMed.
- Proteolytic and non-proteolytic mechanisms of keratin degradation inApplied and environmental microbiology · 2025Article
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Authors and funding
3 authors.
Funding
Abstract
objectiveOnygena corvina is a non-pathogenic, saprophytic fungus that colonizes feathers, hooves, and hair, and represents a valuable source of keratin-degrading enzymes. The only genome assembly of O. corvina available to date was obtained for the strain CBS 281.48 using Illumina short-read sequencing, yielding a reference genome composed of 521 contigs with a contig N50 of 0.229 Mb.
resultsHere, we report an improved O. corvina CBS 281.48 genome assembly generated using a high-quality hybrid approach that combines Illumina short-read and Oxford Nanopore long-read sequencing. The new assembly consists of only 13 contigs totaling 21.8 Mb, with an N50 of 4.4 Mb, and has a completeness of 98.4%. A total of 7,232 protein-coding genes were annotated using an integrative approach that combines de novo predictions, homology-based inferences, and RNA-sequencing–guided evidence. Notably, 158 putative protease-coding genes were identified representing a substantial increase from the 73 predicted proteases in the previous annotation. Our improved genome assembly and associated gene annotations will facilitate comparative genomics, and high-resolution mapping of transcriptomic and proteomic data, to advance research on fungal physiology and fungal abilities to degrade recalcitrant substrates such as keratin.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.