Evidence map›Paper›PMID 41345855›Full record

ArticleAmerican journal of botany2025

Pangenomes as a framework for adaptive radiation, speciation, and adaptation.

Nicolò Tellini, Ole K Tørresen, David Edwards, Loren H Rieseberg, Kjetill S Jakobsen, José Cerca

Abstract read
In one paragraph

Article in American journal of botany, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Nicolò TelliniCNRS, INSERM, IRCAN, Côte d'Azur University, Nice, France.ORCID 0000-0002-2406-2906
Ole K TørresenCentre for Ecological and Evolutionary Synthesis (CEES), Department of Biosciences, University of Oslo, Oslo, Norway.ORCID 0000-0002-1932-8212
David EdwardsCentre for Applied Bioinformatics and School of Biological Sciences, University of Western Australia, Perth, WA, Australia.ORCID 0000-0001-7599-6760
Loren H RiesebergDepartment of Botany and Biodiversity Research Centre, University of British Columbia, Vancouver, V6T 1Z4, BC, Canada.ORCID 0000-0002-2712-2417
Kjetill S JakobsenCentre for Ecological and Evolutionary Synthesis (CEES), Department of Biosciences, University of Oslo, Oslo, Norway.ORCID 0000-0002-8861-5397
José CercaCentre for Ecological and Evolutionary Synthesis (CEES), Department of Biosciences, University of Oslo, Oslo, Norway.ORCID 0000-0001-7788-4367

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Understanding the genomic basis of diversification is a central goal in evolutionary biology. In recent years, the development and use of pangenomes, a genomic representation of multiple individuals within a lineage (a set of related populations, subspecies, ecotypes, or species), has enabled researchers to differentiate between DNA sequences shared by all individuals of a given lineage (core regions) from those present only in some individuals (accessory or variable regions). Differentiating between core and accessory regions has highlighted a key limitation of relying on a single reference genome: It captures the genetic code of only one individual and this biases genomic analyses and our understanding of diversification. Here, we propose that by identifying genes associated with both core and accessory regions, we can deepen our understanding of the processes underlying diversification. We suggest that analyzing pangenomes and accessory regions will provide deeper insights into diversification, hybridization, and the genetic basis of adaptation and speciation.

Indexed as

Adaptation, BiologicalAdaptation, PhysiologicalGenetic SpeciationGenome, PlantPlantsaccessory genomeadaptive radiationgenome adaptationpangenomeplant evolutionspeciationstructural variation

Identifiers

PMID41345855
PMCPMC12712766

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.