Evidence map›Paper›PMID 41345826›Full record

ArticleBMC cardiovascular disorders2025

4D echocardiographic detection of early right atrial and ventricular dysfunction following dual-chamber pacing.

Ganesh G Kamath, Krishnananda Nayak, Mukund A Prabhu, Sridevi Prabhu, Umesh Pai, Karthik A Naik

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In one paragraph

Article in BMC cardiovascular disorders, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

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Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

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5 · Who and what money

Authors and funding

6 authors.

Ganesh G KamathDepartment of Allied Health Professions, Sikkim Manipal Institute of Medical Sciences, Sikkim Manipal University, Gangtok, Sikkim, 737102, India.ORCID 0009-0000-7292-6214
Krishnananda NayakDepartment of Cardiovascular Technology, Manipal College of Health Professions, Manipal Academy of Higher Education, Manipal, Karnataka, 576104, India. krishnananda.n@manipal.edu.ORCID 0000-0001-7376-0834
Mukund A PrabhuDepartment of Cardiology (Electrophysiology Division), Kasturba Medical College, Manipal Academy of Higher Education, Manipal, Karnataka, 576104, India.ORCID 0000-0001-9908-2891
Sridevi PrabhuDepartment of Cardiovascular Technology, Manipal College of Health Professions, Manipal Academy of Higher Education, Manipal, Karnataka, 576104, India.
Umesh PaiDepartment of Cardiovascular Technology, Manipal College of Health Professions, Manipal Academy of Higher Education, Manipal, Karnataka, 576104, India.
Karthik A NaikDepartment of Cardiovascular Technology, Manipal College of Health Professions, Manipal Academy of Higher Education, Manipal, Karnataka, 576104, India.ORCID 0009-0007-3478-7699

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundAlthough the influence of pacing on left ventricular function is well documented, the effect of right ventricular (RV) pacing, particularly concerning lead location (septal vs. apical), on RV function remains underexplored. Furthermore, there is a lack of literature regarding right atrial (RA) remodelling and functional changes following pacemaker implantation. PURPOSE: To assess the effect of a dual-chamber pacemaker on RA and RV structure and function, and their correlation with the site of RV lead positioning using 4D echocardiography.

methodsThis prospective study evaluated 22 patients undergoing permanent dual-chamber pacemaker implantation. Comprehensive clinical and transthoracic echocardiographic assessments were performed at three time points: pre-implantation, pre-discharge, and at the 3-month follow-up. RV function was quantified using tricuspid annular plane systolic excursion, myocardial performance index, global longitudinal strain, and 3D RV ejection fraction. RA function was assessed for reservoir, conduit, and contractile phases using strain analysis. All echocardiographic measurements were conducted by a single echocardiographer utilizing the 4D Vivid S70N system. Device programming parameters were recorded postoperatively.

resultsAlthough conventional parameters remained within the normal range, functionally, a decline in RA reservoir and conduit strain (p = 0.01 and p = 0.02, respectively) and RV GLS (p < 0.001) was observed. TR severity also worsened in nearly 40% of patients compared to baseline (p < 0.001). All patients had a pacing burden greater than 80%.

conclusionRA and RV structural and functional changes begin within 3 months, irrespective of lead site, although non-septal sites exhibited a greater impairment.

Indexed as

Atrial Function, RightAtrial RemodelingCardiac Pacing, ArtificialPacemaker, ArtificialVentricular Dysfunction, RightVentricular Function, RightAgedAged, 80 and overEchocardiographyFemaleHumansMaleMiddle AgedPredictive Value of TestsProspective StudiesTime Factors4D echocardiographyDual-chamber pacemakerRight atrial strainRight ventricular functionTricuspid regurgitation

Identifiers

PMID41345826
PMCPMC12798096

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.