ArticleEsophagus : official journal of the Japan Esophageal Society2026
Preoperative low attenuation area percentage as a predictor of postoperative pulmonary complications and prognosis in esophagectomy: a retrospective cohort study.
Article in Esophagus : official journal of the Japan Esophageal Society, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
3 citing papers in PubMed.
- Factors associated with marked reduction in tongue pressure in patients with esophageal cancer during neoadjuvant chemotherapy.Esophagus : official journal of the Japan Esophageal Society · 2026Article
- Comparative clinical utility of preoperative psoas muscle and skeletal muscle index cutoffs for risk stratification after esophagectomy.Surgery today · 2026Article
- Identification and validation of an explainable machine learning model for early postoperative pulmonary complications after esophagectomy in patients with esophageal cancer.Journal of gastrointestinal oncology · 2026Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
8 authors.
Funding
Abstract
backgroundPostoperative pulmonary complications (PPCs) significantly influence clinical outcomes following esophagectomy for esophageal cancer. Identifying reliable preoperative predictors is essential for optimizing surgical outcomes. Although chronic obstructive pulmonary disease (COPD) is an established risk factor, the role of preoperative quantitative emphysema assessment using low-attenuation area percentage (LAA%) on computed tomography (CT) remains unclear. We retrospectively investigated the association of preoperative LAA% with PPCs and postoperative prognosis in patients undergoing thoracic esophagectomy for esophageal cancer.
methodsWe enrolled 334 patients who underwent esophagectomy for esophageal cancer at Kindai University Hospital between January 2016 and March 2024. Preoperative LAA% was quantified using specialized software, and PPCs were defined as events occurring within 2 weeks after esophagectomy and classified according to the Clavien-Dindo classification. The association between bilateral LAA% and PPCs was assessed using logistic regression analyses, while long-term prognosis was evaluated using Kaplan-Meier survival analysis.
resultsThe incidence of PPCs was 32.9% (110/334 patients). Multivariable logistic regression analysis demonstrated that preoperative bilateral LAA% ≥ 5% was significantly associated with an increased risk of PPCs (odds ratio [OR]: 3.81, 95% confidence interval [CI] 1.01-14.4, p = 0.04). Kaplan-Meier survival analysis showed that patients with bilateral LAA% ≥ 5% had significantly lower 5-year overall survival than those with bilateral LAA% < 5% (p = 0.03).
conclusionPreoperative LAA% is a predictor of PPCs and postoperative prognosis after esophagectomy for esophageal cancer. Quantitative CT analysis of emphysema can improve the preoperative risk stratification. Future multicenter studies are needed to validate these results, particularly for minimally invasive esophagectomies.
Indexed as
Identifiers
41345762What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.