Evidence map›Paper›PMID 41345724›Full record

ArticleBorderline personality disorder and emotion dysregulation2025

Subgroups of emotion dysregulation in adults: a latent profile analysis in a clinically heterogeneous population.

Martin Blay, Amaury Durpoix, Mario Speranza, Roland Hasler, Rosetta Nicastro, Eleonore Pham, Eva Rüfenacht, Luisa Weiner, Sébastien Weibel, Martin Debbane and 1 more

Abstract read
In one paragraph

Article in Borderline personality disorder and emotion dysregulation, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

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0cells of the map it votes in
1citing papers in PubMed
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1 · What the graph read from it

What it found

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2 · The registry

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3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

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4 · The record

Corrections and comments

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5 · Who and what money

Authors and funding

11 authors.

Martin BlayADDIPSY, Addictology and Psychiatry Oupatient Center, Santé Basque Développement group, Lyon, France. martin.blay5@gmail.com.ORCID http://orcid.org/0000-0001-7021-1768
Amaury DurpoixUniversity Hospitals of Strasbourg, Strasbourg, France.
Mario SperanzaUniversité Paris-Saclay, UVSQ, INSERM, Centre de recherche en Epidémiologie et Santé des Populations Team DevPsy, Villejuif, 94807, France.
Roland HaslerService of Psychiatric Specialties, Department of Psychiatry, University Hospitals of Geneva, Geneva, Switzerland.
Rosetta NicastroService of Psychiatric Specialties, Department of Psychiatry, University Hospitals of Geneva, Geneva, Switzerland.
Eleonore PhamService of Psychiatric Specialties, Department of Psychiatry, University Hospitals of Geneva, Geneva, Switzerland.
Eva RüfenachtService of Psychiatric Specialties, Department of Psychiatry, University Hospitals of Geneva, Geneva, Switzerland.
Luisa WeinerUniversity Hospitals of Strasbourg, Strasbourg, France.
Sébastien WeibelUniversity Hospitals of Strasbourg, Strasbourg, France.
Martin DebbaneDevelopmental Clinical Psychology Research Unit, Faculty of Psychology and Educational Sciences, University of Geneva, Geneva, Switzerland.
Nader PerroudService of Psychiatric Specialties, Department of Psychiatry, University Hospitals of Geneva, Geneva, Switzerland. nader.perroud@unige.ch.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundEven if it was first described in borderline personality disorder, emotion dysregulation (ED) is increasingly recognized as a transdiagnostic and dimensional construct, best understood along a continuum of severity rather than as a discrete category. Prior cluster-analytic studies have consistently explored heterogeneity within this continuum by identifying patient subgroups, but most were conducted in populations defined by specific diagnostic categories, limiting their generalizability. To better capture ED's core components, studies conducted in clinically heterogeneous adult populations are needed.

methodsIn this context, we conducted a latent profile analysis on 349 adults referred for ED-related difficulties at a specialized outpatient clinic. Profiles were derived from the six subscales of the Difficulties in Emotion Regulation Scale. Patients were assessed on sociodemographic variables, emotion regulation difficulties and strategies, mentalizing abilities, comorbid psychopathology, and well-being.

resultsA two-class solution was retained. Subgroups did not align with any specific diagnostic category but rather emerged along a severity continuum. Cluster 1 (n = 267) was characterized by more severe ED in every domain, higher use of non-adaptive regulation strategies, lower self-mentalizing abilities, greater comorbid psychopathology, and lower well-being. Cluster 2 (n = 82) displayed comparatively preserved emotion regulation abilities and strategies, higher self-mentalizing, fewer comorbidities, and greater well-being.

conclusionsOur findings provide further evidence for the existence and characterization of subgroups in patients with ED, reflecting gradations along a severity continuum. While exploratory, they also suggest that core mechanisms targeted by DBT and MBT (i.e., maladaptive emotion regulation strategies and self-mentalizing abilities) may be relevant therapeutic targets across a broader transdiagnostic spectrum.

Indexed as

DimensionalEmotion dysregulationLatent profile analysisPsychotherapyTransdiagnostic

Identifiers

PMID41345724
PMCPMC12679781

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.