Evidence map›Paper›PMID 41345669›Full record

Trial reportCritical care (London, England)2025

Influence of different airway devices on intra-arrest ventilation during bag-valve-device ventilation - a prospective randomized controlled cadaver study.

Jonas Lohmann, Beate Brand-Saberi, Mahsa Ullrich, Tamar Gelashvili, Annika Hoyer, Lydia Johnson Kolaparambil Varghese, Vanessa Kuehn, Christian Neuhaus, Claudia Schneider, Justin Trenkel and 2 more

Registry-linked trialAbstract readRandomized Controlled Trial
In one paragraph

Trial report in Critical care (London, England), 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT06306898 (Intra-Arrest-Ventilation - a Prospective Randomized Trial in Human Cadavers), which is not on this map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT06306898 nacompletednot on this map

Intra-Arrest-Ventilation - a Prospective Randomized Trial in Human Cadavers

TypeinterventionalSponsorGerrit JansenRan2024 to 2024Enrolled10ConditionsCardiac ArrestArmsEndotracheal Intubation, Laryngeal tube, Laryngeal mask, I-Gel-Laryngeal Mask
3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Trial
  2. Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Jonas LohmannMedical School OWL, Bielefeld University, Universitätsstraße 25, 33615, Bielefeld, Germany. Jonas.lohmann@uni-bielefeld.de.
Beate Brand-SaberiDepartment of Anatomy and Molecular Embryology, Institute of Anatomy, Medical Faculty of Ruhr University Bochum, Ruhr University Bochum, Universitätstraße 150, 44801, Bochum, Germany.
Mahsa UllrichWEINMANN Emergency Medical Technology GmbH + Co. KG, Frohbösestraße 12, 22525, Hamburg, Germany.
Tamar GelashviliUniversity Department of Anesthesiology, Intensive Care Medicine, Emergency Medicine and Pain Medicine, Johannes Wesling Klinikum Minden, Ruhr University Bochum, Hans- Nolte-Straße 1, 32429, Minden, Germany.
Annika HoyerMedical School OWL, Biostatistics and Medical Biometry, Bielefeld University, Universitätsstraße 25, 33615, Bielefeld, Germany.
Lydia Johnson Kolaparambil VargheseUniversity Department of Anesthesiology, Intensive Care Medicine, Emergency Medicine and Pain Medicine, Johannes Wesling Klinikum Minden, Ruhr University Bochum, Hans- Nolte-Straße 1, 32429, Minden, Germany.
Vanessa KuehnWEINMANN Emergency Medical Technology GmbH + Co. KG, Frohbösestraße 12, 22525, Hamburg, Germany.
Christian NeuhausWEINMANN Emergency Medical Technology GmbH + Co. KG, Frohbösestraße 12, 22525, Hamburg, Germany.
Claudia SchneiderDepartment of Anatomy and Molecular Embryology, Institute of Anatomy, Medical Faculty of Ruhr University Bochum, Ruhr University Bochum, Universitätstraße 150, 44801, Bochum, Germany.
Justin TrenkelDepartment of Anatomy and Molecular Embryology, Institute of Anatomy, Medical Faculty of Ruhr University Bochum, Ruhr University Bochum, Universitätstraße 150, 44801, Bochum, Germany.
Jochen HinkelbeinUniversity Department of Anesthesiology, Intensive Care Medicine, Emergency Medicine and Pain Medicine, Johannes Wesling Klinikum Minden, Ruhr University Bochum, Hans- Nolte-Straße 1, 32429, Minden, Germany.
Gerrit JansenUniversity Department of Anesthesiology, Intensive Care Medicine, Emergency Medicine and Pain Medicine, Johannes Wesling Klinikum Minden, Ruhr University Bochum, Hans- Nolte-Straße 1, 32429, Minden, Germany.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundOut-of-hospital cardiac arrest remains a major challenge due to its high incidence and low survival rates. In recent decades, research has focused on the performance of chest compressions and improvements in early defibrillation, while the optimal ventilation strategy remains unclear. Despite the lack of monitoring systems, manual bag-valve-device ventilation is still common. Given the potential impact of both the applied volumes and the ventilation pressures on hemodynamics and resuscitation efforts, the present study investigated the effects of various airway devices on the target parameters of ventilation therapy during manual intra-arrest ventilation.

methodsThiel-embalmed human cadavers were included in a standardized resuscitation scenario. Ventilation was performed in a randomized order using various airway devices (tracheal tube (ET), supraglottic airway devices (SGA): laryngeal mask airway, laryngeal tube, i-gel

resultsEleven cadavers were included (mean age at the time of death: 84 ± 3.7 years, male = 7 [63.6%]). During ventilation with ET, the following mean values were measured: ΔVt, 142.2 ± 125.5 ml; Vt

conclusionThe ∆Vt was lower in the ET group than the SGA group, whereas there was no evidence for differences in ∆Vt among the devices in the SGA group.

trial registrationclinicaltrials.gov; Unique identifier: NCT06306898, Registration date: 5 March 2024.

Indexed as

Airway ManagementRespiration, ArtificialAgedCadaverCardiopulmonary ResuscitationEquipment DesignFemaleHumansIntubation, IntratrachealLaryngeal MasksMaleProspective StudiesAdvanced Cardiac Life SupportAirway managementResuscitationVentilation, artificial

Identifiers

PMID41345669
PMCPMC12681136

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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.