Evidence map›Paper›PMID 41345606›Full record

ArticleBMC musculoskeletal disorders2025

Severity-dependent benefits of AI-assisted 3D planning in total hip arthroplasty: a Crowe I-IV subgroup and trend analysis.

Zhenbao Lu, Qijin Wang, Xu Wang, Qingshan Xu, Yuhua Feng, Jiliang Chen, Xiaolu Wang, Jianfu Zhu, Jinqing Wu, Tihui Wang and 3 more

Abstract readComparative Study
In one paragraph

Article in BMC musculoskeletal disorders, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors.

Zhenbao Lu *Department of Orthopedics, Affiliated Mindong Hospital, Fujian Medical University, Ningde, Fujian, China.
Qijin Wang *Department of Orthopedics, Affiliated Mindong Hospital, Fujian Medical University, Ningde, Fujian, China.
Xu WangDepartment of Orthopedics, Affiliated Mindong Hospital, Fujian Medical University, Ningde, Fujian, China.
Qingshan XuDepartment of Orthopedics, Affiliated Mindong Hospital, Fujian Medical University, Ningde, Fujian, China.
Yuhua FengDepartment of Orthopedics, Affiliated Mindong Hospital, Fujian Medical University, Ningde, Fujian, China.
Jiliang ChenDepartment of Orthopedics, Affiliated Mindong Hospital, Fujian Medical University, Ningde, Fujian, China.
Xiaolu WangDepartment of Orthopedics, Affiliated Mindong Hospital, Fujian Medical University, Ningde, Fujian, China.
Jianfu ZhuDepartment of Orthopedics, Affiliated Mindong Hospital, Fujian Medical University, Ningde, Fujian, China.
Jinqing WuDepartment of Orthopedics, Affiliated Mindong Hospital, Fujian Medical University, Ningde, Fujian, China.
Tihui WangDepartment of Orthopedics, Affiliated Mindong Hospital, Fujian Medical University, Ningde, Fujian, China.
Qiujin XiaDepartment of Orthopedics, Affiliated Mindong Hospital, Fujian Medical University, Ningde, Fujian, China.
Xiaohong FanSchool of New Energy and Intelligent Manufacturing, Ningde Vocational and Technical College, Ningde, Fujian, China. fxhxiaohong@126.com.
Cuihua YuanDepartment of Orthopedics, Affiliated Mindong Hospital, Fujian Medical University, Ningde, Fujian, China. drcuihuayuan@163.com.

Funding

Natural Science Foundation of Fujian Province 2025J011687
6 · The paper itself

Abstract

purposeTo compare AI-assisted 3D (AI-3D) preoperative planning versus two-dimensional (2D) X-ray preoperative planning for total hip arthroplasty (THA) using subgroup analyses (Crowe I-II vs. III-IV), and to examine associations between deformity severity and both planning accuracy and clinical outcomes via ordered trend analyses.

methodsSingle-centre retrospective cohort including 116 consecutive patients undergoing THA (May 2020-July 2023; AI-3D n = 61; 2D X-ray n = 55). Co-primary endpoints were exact implant size-match (cup/stem) and acetabular safe-zone attainment (Lewinnek/Callanan); Secondary endpoints included operative time, estimated blood loss, postoperative leg-length discrepancy (LLD), and 24-month functional scores-Harris Hip Score (HHS), Western Ontario and McMaster Universities Osteoarthritis Index (WOMAC), and pain on a visual analog scale (VAS)-plus implant survivorship. Analyses compared AI-3D versus 2D within prespecified Crowe subgroups; ordered trend tests across I-IV were performed in the pooled cohort.

resultsOverall comparisons showed that AI-3D demonstrated significantly higher accuracy in sizing prediction and acetabular cup positioning in this study: cup size-match 63.9% versus 41.8% (P = 0.017), stem size-match 65.6% versus 47.3% (P = 0.047), and Lewinnek/Callanan safe-zone attainment 91.8% versus 76.4% (P = 0.021); by contrast, operative time and blood loss did not differ significantly. Subgroup analyses suggested that this benefit was mainly confined to Crowe I-II, while in Crowe III-IV the differences were not significant. At the 24-month follow-up, HHS, WOMAC, VAS, and implant survivorship (≈ 98%) were comparable between groups. In trend analyses pooling both cohorts, cup match rates decreased as Crowe grade increased (P = 0.004), the extent of functional improvement (change in HHS (ΔHHS), change in WOMAC (ΔWOMAC)) rose with greater deformity severity (both P ≤ 0.001), and safe-zone attainment remained high without a clear monotonic trend.

conclusionsAI-3D preoperative planning provides measurable gains in implant sizing and acetabular cup positioning for THA, with benefits most evident in mild-to-moderate deformities (Crowe I-II). In severe deformities (Crowe III-IV), anatomical and reconstructive challenges appear to limit these advantages, emphasizing the continued importance of surgical expertise. Functional outcomes were comparable between AI-3D and conventional 2D planning. Overall, AI-3D may serve as a useful adjunct in complex cases, pending confirmation in larger multicentre and long-term studies.

Indexed as

Arthroplasty, Replacement, HipImaging, Three-DimensionalOsteoarthritis, HipSurgery, Computer-AssistedAgedFemaleHip ProsthesisHumansMaleMiddle AgedPattern Analysis, MachineRetrospective StudiesSeverity of Illness IndexTreatment OutcomeArtificial intelligenceCrowe classificationDevelopmental dysplasia of the hipSeptic arthritis sequelaeThree-dimensional planningTotal hip arthroplasty

Identifiers

PMID41345606
PMCPMC12676770

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.